• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

关节腔内注射类固醇后出现下丘脑-垂体-肾上腺轴受抑制的库欣综合征。

Cushing's syndrome with suppression of the hypothalamic-pituitary-adrenal axis after intra-articular steroid injections.

作者信息

O'Sullivan M M, Rumfeld W R, Jones M K, Williams B D

出版信息

Ann Rheum Dis. 1985 Aug;44(8):561-3. doi: 10.1136/ard.44.8.561.

DOI:10.1136/ard.44.8.561
PMID:4026419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001703/
Abstract

A case of Cushing's syndrome after long term intra-articular corticosteroid injections is described. Prolonged suppression of the hypothalamic-pituitary-adrenal axis occurred as assessed by an insulin tolerance test 11 weeks after the last intra-articular injection. Replacement steroid therapy was required.

摘要

本文描述了一例长期关节腔内注射皮质类固醇后发生库欣综合征的病例。在最后一次关节腔内注射11周后，通过胰岛素耐量试验评估发现下丘脑-垂体-肾上腺轴受到长期抑制，因此需要进行类固醇替代治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d560/1001703/ae860cae6109/annrheumd00263-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d560/1001703/ae860cae6109/annrheumd00263-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d560/1001703/ae860cae6109/annrheumd00263-0062-a.jpg

相似文献

1
Cushing's syndrome with suppression of the hypothalamic-pituitary-adrenal axis after intra-articular steroid injections.关节腔内注射类固醇后出现下丘脑-垂体-肾上腺轴受抑制的库欣综合征。
Ann Rheum Dis. 1985 Aug;44(8):561-3. doi: 10.1136/ard.44.8.561.
2
Cushing's syndrome after intra-articular and intradermal administration of triamcinolone acetonide in three pediatric patients.三名儿科患者关节内和皮内注射曲安奈德后发生库欣综合征。
Pediatrics. 2004 Jun;113(6):1820-4. doi: 10.1542/peds.113.6.1820.
3
A prospective observational study evaluating hypothalamic-pituitary-adrenal axis alteration and efficacy of intramuscular triamcinolone acetonide for steroid-responsive dermatologic disease.一项评估下丘脑-垂体-肾上腺轴改变和肌肉注射曲安奈德治疗皮质类固醇反应性皮肤病疗效的前瞻性观察性研究。
J Am Acad Dermatol. 2013 Aug;69(2):226-31. doi: 10.1016/j.jaad.2013.02.005. Epub 2013 Mar 30.
4
Cushing's syndrome and hypothalamic-pituitary adrenal axis suppression induced by medroxyprogesterone acetate.醋酸甲羟孕酮所致库欣综合征及下丘脑-垂体-肾上腺轴抑制
Ann Clin Biochem. 1996 May;33 ( Pt 3):187-9. doi: 10.1177/000456329603300302.
5
Glucocorticoid resorption and influence on the hypothalamic-pituitary-adrenal axis after intra-articular treatment of the knee in resting and mobile patients.静息和活动患者膝关节腔内治疗后糖皮质激素的吸收及其对下丘脑-垂体-肾上腺轴的影响
Ann Rheum Dis. 2006 Jul;65(7):955-7. doi: 10.1136/ard.2005.041525.
6
Hypothalamo-pituitary-adrenal axis in iatrogenic Cushing's syndrome.
Taiwan Yi Xue Hui Za Zhi. 1985 Aug;84(8):936-43.
7
Prolonged childhood Cushing's syndrome secondary to intralesional triamcinolone acetonide.病灶内注射曲安奈德所致的儿童期长期库欣综合征
Ann Trop Paediatr. 2002 Mar;22(1):89-91. doi: 10.1179/027249302125000229.
8
Systemic effects of intra-articular steroid preparations.关节内注射类固醇制剂的全身效应。
Ann Rheum Dis. 1980 Aug;39(4):413-4. doi: 10.1136/ard.39.4.413.
9
Iatrogenic Cushing's syndrome and secondary adrenal insufficiency after a single intra-articular administration of triamcinolone acetonide in HIV-infected patients treated with ritonavir.在接受利托那韦治疗的HIV感染患者中，单次关节腔内注射曲安奈德后发生医源性库欣综合征和继发性肾上腺功能不全。
Clin Rheumatol. 2008 Dec;27 Suppl 2:S79-82. doi: 10.1007/s10067-008-1022-x. Epub 2008 Oct 1.
10
Systemic effects of intraarticular administration of triamcinolone hexacetonide.关节腔内注射己曲安奈德的全身效应。
Isr J Med Sci. 1983 Jan;19(1):83-4.

引用本文的文献

1
[Cushing's syndrome with subsequent tertiary adrenocortical insufficiency after simultaneous multiple intra-articular local glucocorticoid treatment : Keep an eye on hormone deficiency conditions requiring treatment after multiple administrations of local steroids].同时多次关节腔内局部应用糖皮质激素后发生库欣综合征并继发三发性肾上腺皮质功能不全：关注多次局部应用类固醇激素后需要治疗的激素缺乏情况
Z Rheumatol. 2021 Oct;80(8):771-775. doi: 10.1007/s00393-021-01000-8. Epub 2021 Apr 22.
2
Effects of intra-articular corticosteroid injections on lumbar trabecular density.关节内皮质类固醇注射对腰椎小梁密度的影响。
Skeletal Radiol. 2020 May;49(5):787-793. doi: 10.1007/s00256-019-03362-2. Epub 2019 Dec 13.
3

本文引用的文献

1
The effect of intra-articular injection of cortisone acetate and of hydrocortisone acetate in rheumatoid arthritis.关节内注射醋酸可的松和醋酸氢化可的松对类风湿性关节炎的疗效。
Clin Sci. 1953 Feb;12(1):15-31.
2
Serum methylprednisolone levels following intra-articular injection of methylprednisolone acetate.关节腔内注射醋酸甲泼尼龙后的血清甲泼尼龙水平。
Ann Rheum Dis. 1981 Dec;40(6):571-4. doi: 10.1136/ard.40.6.571.
3
Local corticosteroid injection treatment in rheumatic disorders.局部皮质类固醇注射治疗风湿性疾病。
Intra-articular corticosteroids in the treatment of juvenile idiopathic arthritis: Safety, efficacy, and features affecting outcome. A comprehensive review of the literature.
关节内注射皮质类固醇治疗幼年特发性关节炎：安全性、有效性及影响疗效的因素。文献综述
Open Access Rheumatol. 2009 May 14;1:37-49. doi: 10.2147/oarrr.s5103. eCollection 2009.
4
Intra-articular glucocorticoid injections and their effect on hypothalamic-pituitary-adrenal (HPA)-axis function.关节内注射糖皮质激素及其对下丘脑-垂体-肾上腺（HPA）轴功能的影响。
Endocrine. 2015 Mar;48(2):410-6. doi: 10.1007/s12020-014-0409-5. Epub 2014 Sep 3.
5
Cushing's syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars.曲安奈德皮损内注射后并发库欣综合征和肾上腺皮质功能不全致瘢痕疙瘩。
Eur J Pediatr. 2010 Sep;169(9):1147-9. doi: 10.1007/s00431-010-1165-z. Epub 2010 Feb 26.
6
Systemic effects of intra-articular corticosteroids.关节内注射皮质类固醇的全身效应。
Clin Rheumatol. 2009 Jul;28(7):749-56. doi: 10.1007/s10067-009-1135-x. Epub 2009 Feb 28.
7
The effect of local corticosteroid or ketorolac exposure on histologic and biomechanical properties of rabbit tendon and cartilage.局部使用皮质类固醇或酮咯酸对兔肌腱和软骨的组织学及生物力学特性的影响。
Hand (N Y). 2007 Dec;2(4):165-72. doi: 10.1007/s11552-007-9042-6. Epub 2007 May 5.
8
Glucocorticoid resorption and influence on the hypothalamic-pituitary-adrenal axis after intra-articular treatment of the knee in resting and mobile patients.静息和活动患者膝关节腔内治疗后糖皮质激素的吸收及其对下丘脑-垂体-肾上腺轴的影响
Ann Rheum Dis. 2006 Jul;65(7):955-7. doi: 10.1136/ard.2005.041525.
9
Acute and persistent iatrogenic Cushing's syndrome after a single dose of triamcinolone acetonide.单次注射曲安奈德后发生的急性和持续性医源性库欣综合征
J Endocrinol Invest. 2005 Dec;28(11):1019-23. doi: 10.1007/BF03345342.
10
Shrinkage of the pituitary gland following steroid therapy in a patient with Tolosa-Hunt syndrome.托洛萨-亨特综合征患者接受类固醇治疗后垂体萎缩。
Neuroradiology. 1993;35(6):449-50. doi: 10.1007/BF00602827.
Semin Arthritis Rheum. 1981 May;10(4):231-54. doi: 10.1016/0049-0172(81)90001-9.
4
Intra-articular corticosteroids. An updated assessment.关节内注射皮质类固醇。最新评估。
Clin Orthop Relat Res. 1983 Jul-Aug(177):235-63.
5
A new intra-articular steroid with prolonged anti-inflammatory action.一种具有延长抗炎作用的新型关节内类固醇。
Minn Med. 1967 Apr;50(4):483-6.
6
Triamcinolone hexacetonide. A new corticosteroid for intra-articular therapy.己曲安奈德。一种用于关节内治疗的新型皮质类固醇。
Ann Phys Med. 1967 May;9(2):55-8.
7
The systemic effects of intra-articular corticosteroid.关节内注射皮质类固醇的全身效应。
J Rheumatol. 1974 Mar;1(1):117-25.
8
Repeated corticosteroid injections into knee joints.
Rheumatol Rehabil. 1977 Aug;16(3):137-40. doi: 10.1093/rheumatology/16.3.137.