Department of Pediatrics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
Eur J Pediatr. 2010 Sep;169(9):1147-9. doi: 10.1007/s00431-010-1165-z. Epub 2010 Feb 26.
A 6-year-old girl was admitted to our hospital for excessive weight gain. On presentation, she had a typical Cushingoid appearance and hypertension. Laboratory analysis was indicative for an exogenous glucocorticoid source, showing values that were low for serum cortisol and adrenocorticotropin and for 24-h urinary glucocorticoid (metabolite) excretion. Five and 2 months before presentation, she was treated with intradermal triamcinolone acetonide for keloid scars. Recovery of intrinsic cortisol production occurred 12 months after the last steroid dose. Intradermal triamcinolone acetonide for keloid scars in children should be used with care taking into account the here reported complication.
一位 6 岁女孩因体重过度增加而被收入我院。就诊时，她表现出典型的库欣样外观和高血压。实验室分析提示外源性糖皮质激素来源，血清皮质醇和促肾上腺皮质激素以及 24 小时尿糖皮质激素（代谢物）排泄值均较低。在就诊前 5 个月和 2 个月时，她因瘢痕疙瘩接受了曲安奈德的皮内注射治疗。末次类固醇剂量后 12 个月，内源性皮质醇生成恢复。在考虑到此处报告的并发症的情况下，应谨慎使用曲安奈德皮内注射治疗儿童瘢痕疙瘩。
