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:口腔感染患者菌血症的病例研究中的致病潜力

The Pathogenic Potential of : A Case Study of Bacteremia in a Patient With Oral Infection.

作者信息

Zhou Gang, Cornelius Lisa, Navarathna Dhammika H

机构信息

Department of Pathology and Laboratory Medicine, Baylor Scott and White Medical Center, Temple, Texas, USA.

Department of Medicine, Central Texas Veterans Healthcare System, Temple, Texas, USA.

出版信息

Case Rep Infect Dis. 2025 Apr 15;2025:2079663. doi: 10.1155/crdi/2079663. eCollection 2025.

Abstract

is an anaerobic, Gram-positive, nonspore-forming bacterium that is typically part of the normal oral microbiota. It is generally considered biochemically inert and is often dismissed as a nonpathogenic contaminant in clinical cultures, particularly in respiratory samples. However, in this case study, we report a rare instance of . bacteremia in a patient with multiple medical comorbidities who was hospitalized after reporting to Emergency Department due to fatigue and right ear pain. The patient subsequently developed signs of persistent symptoms of septicemia, prompting an extensive investigation. Blood cultures identified . as the causative agent. This case underscores the importance of thorough culture workup and clinical correlation, especially in immunocompromised patients and patients with multiple medical comorbidities. Comprehensive dental care and the administration of targeted antibiotic therapy resulted in the patient's full recovery. This report highlights the potential pathogenic role of . in certain clinical scenarios and emphasizes the need for awareness of its possible implications in systemic infections.

摘要

是一种厌氧、革兰氏阳性、不形成芽孢的细菌,通常是正常口腔微生物群的一部分。它一般被认为生化活性低,在临床培养中常被当作非致病性污染物而不予考虑,尤其是在呼吸道样本中。然而,在本病例研究中,我们报告了一例罕见的菌血症病例,患者有多种内科合并症,因疲劳和右耳疼痛到急诊科就诊后住院。该患者随后出现败血症持续症状的体征,促使进行了广泛调查。血培养确定为病原体。本病例强调了全面培养检查和临床关联的重要性,尤其是在免疫功能低下患者和有多种内科合并症的患者中。全面的牙科护理和针对性抗生素治疗使患者完全康复。本报告突出了在某些临床情况下的潜在致病作用,并强调需要认识到其在全身感染中可能产生的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dcf/12014268/2151009a9f3c/CRIID2025-2079663.001.jpg

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