Carreiro-Martins Pedro, Caires Iolanda, Almeida Isabel, Afonso Ricardo A, Dezerto Raquel, Tomé André, Rodrigues Ana M, Henriques Ana Rita, Neuparth Nuno
Comprehensive Health Research Centre, LA-REAL, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.
Serviço de Imunoalergologia, ULS São José, Lisbon, Portugal.
ERJ Open Res. 2025 Apr 22;11(2). doi: 10.1183/23120541.00887-2024. eCollection 2025 Mar.
Chronic cough is associated with high individual and social costs, mainly due to doctor visits and diagnostic investigations. The aim of the present study was to estimate the prevalence of chronic cough and identify risk factors associated with chronic cough in a community-based sample in the scope of the EpiCOUGH study.
From 1 June to 31 August 2023, we recruited adults from the largest primary healthcare centres in Lisbon, Portugal, and invited them to participate in an online survey. Participants aged ≥20 years with a registered email address were eligible. Data collection included a health questionnaire that recorded the presence, duration, frequency and impact of cough on daily activities. Chronic cough was defined as lasting longer than 8 weeks.
Of the 7285 adult healthcare users who agreed to participate, 2309 (31.7%) completed the questionnaire. Most were female (59.2%) and the mean±sd age was 51.6±13.5 years. The estimated prevalence of chronic cough was 7.23% (95% CI 6.24-8.36%). Chronic cough was associated with older age, being divorced/widowed, current smoking, obesity, asthma, working in a dusty environment and pet ownership. No cause was diagnosed in 23.36% of patients who consulted a doctor.
Chronic cough was relatively common in the population studied. Our data emphasise the need to treat patients with chronic cough with strategies that address risk factors. This study also highlights the complexity of chronic cough management and the need for further research and diagnostic tools to improve patient outcomes.
慢性咳嗽会给个人和社会带来高昂成本,主要是因为看医生和进行诊断检查。本研究的目的是在EpiCOUGH研究范围内,估计基于社区样本的慢性咳嗽患病率,并确定与慢性咳嗽相关的风险因素。
2023年6月1日至8月31日,我们从葡萄牙里斯本最大的初级医疗保健中心招募成年人,并邀请他们参加在线调查。年龄≥20岁且有注册电子邮件地址的参与者符合条件。数据收集包括一份健康问卷,记录咳嗽的存在情况、持续时间、频率以及对日常活动的影响。慢性咳嗽定义为持续超过8周。
在7285名同意参与的成年医疗用户中,2309人(31.7%)完成了问卷。大多数为女性(59.2%),平均年龄±标准差为51.6±13.5岁。慢性咳嗽的估计患病率为7.23%(95%置信区间6.24 - 8.36%)。慢性咳嗽与年龄较大、离婚/丧偶、当前吸烟、肥胖、哮喘、在多尘环境中工作以及养宠物有关。在看过医生的患者中,23.36%未确诊病因。
在所研究的人群中,慢性咳嗽相对常见。我们的数据强调需要采用针对风险因素的策略来治疗慢性咳嗽患者。本研究还突出了慢性咳嗽管理的复杂性以及需要进一步研究和诊断工具以改善患者预后。