法国慢性咳嗽的患病率及负担
Prevalence and burden of chronic cough in France.
作者信息
Guilleminault Laurent, Li Vicky W, Fonseca Eileen, Martin Ashley, Schelfhout Jonathan, Ding Helen, Le Moine Gaëlle
机构信息
Pôle des Voies Respiratoires, Hôpital Larrey, CHU de Toulouse, Toulouse, France.
Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity) INSERM UMR1291 - CNRS UMR5051 - Université Toulouse III, CRISALIS F-CRIN, Toulouse, France.
出版信息
ERJ Open Res. 2024 Apr 8;10(2). doi: 10.1183/23120541.00806-2023. eCollection 2024 Mar.
BACKGROUND
Chronic cough is a common condition that is associated with lower health-related quality of life and greater healthcare resource use. There are limited data on the prevalence, population characteristics and burden of chronic cough in France.
METHODS
This was a cross-sectional study based on responses from French adult residents to the 2020 National Health and Wellness Survey. Respondents with chronic cough were compared to 1:3 propensity score-matched controls without chronic cough.
RESULTS
The weighted lifetime and 12-month prevalence of chronic cough were estimated as 7.5% and 4.8%, respectively. Respondents with chronic cough reported significantly worse perceived health than matched controls, with lower mean±sd scores of 46.68±9.28 50.42±8.26 on the physical health component and 40.32±9.87 44.32± 9.69 on the mental health component of the Medical Outcomes Study 12-item Short Form Survey Version 2 survey (p0.001 for both comparisons). Respondents with chronic cough also had higher rates of moderate-to-severe forms of anxiety (24.4% 12.4%) and depression (36.4% 20.2%); higher rates of multiple forms of sleep disturbance; greater impairment of work productivity (38.2% 25.5%) and other activities (41.8% 28.2%; p0.001 for all comparisons). Respondents with chronic cough also had higher rates of all-cause healthcare resource use including emergency room visits, hospitalisation, and overall and specialist healthcare provider visits compared to controls (p0.001 for all comparisons).
CONCLUSION
Chronic cough is a common condition in France that is associated with lower health-related quality of life and greater healthcare resource utilisation.
背景
慢性咳嗽是一种常见病症,与较低的健康相关生活质量及更多的医疗资源使用相关。关于法国慢性咳嗽的患病率、人群特征及负担的数据有限。
方法
这是一项横断面研究,基于法国成年居民对2020年国民健康与幸福调查的回答。将患有慢性咳嗽的受访者与1:3倾向得分匹配的无慢性咳嗽对照组进行比较。
结果
慢性咳嗽的加权终生患病率和12个月患病率分别估计为7.5%和4.8%。患有慢性咳嗽的受访者报告的自我感觉健康状况明显比匹配的对照组差,在医学结局研究12项简短问卷第2版调查的身体健康部分,平均±标准差得分分别为46.68±9.28和50.42±8.26,在心理健康部分分别为40.32±9.87和44.32±9.69(两项比较p均<0.001)。患有慢性咳嗽的受访者中度至重度焦虑(24.4%对12.4%)和抑郁(36.4%对20.2%)的发生率也更高;多种形式睡眠障碍的发生率更高;工作生产力受损更严重(38.2%对25.5%)以及其他活动受损更严重(41.8%对28.2%;所有比较p<0.001)。与对照组相比,患有慢性咳嗽的受访者全因医疗资源使用的发生率也更高,包括急诊就诊、住院以及全科和专科医疗服务提供者就诊(所有比较p<0.001)。
结论
慢性咳嗽在法国是一种常见病症,与较低的健康相关生活质量及更高的医疗资源利用相关。