Yusufu Alimujiang, Haibier Abuduwupuer, Ma Yuan
Department of Spine Surgery, The Sixth Affiliated Hospital of Xinjiang Medical University, Orthopaedic Hospital of Xinjiang Uygur Autonomous Region, Urumqi, People's Republic of China.
Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi, People's Republic of China.
Infect Drug Resist. 2025 Apr 18;18:1923-1934. doi: 10.2147/IDR.S496495. eCollection 2025.
This study intends to compare the efficacy and safety of endoscopic lumbar brucellosis with traditional posterior focus debridement, bone grafting, fusion and internal fixation combined with drugs in the treatment of lumbar brucellosis, and summarize the advantages and disadvantages of different surgical methods, in order to provide theoretical support for clinical surgical decision-making.
The data of 41 lumbar brucellosis patients admitted to the Department of spinal Surgery of the Sixth Affiliated Hospital of Xinjiang Medical University from January 2018 to June 2023 were divided into endoscopic group (Group A, n = 15) and open surgery group (Group B, n = 26). Two groups of general data, surgical and related indicators, blood biochemical and imaging indicators were recorded and analyzed, and the clinical recovery and complications were evaluated according to various scores.
There was no statistical difference in baseline data between Group A and Group B, and it could be compared between the two groups; the postoperative lumbar VAS score and hemoglobin index of Group A were significantly better than that of Group B, and the difference was statistically significant (P<0.05); Group A was significantly better than Group B in terms of operation time, intraoperative blood loss and postoperative time to go down, and the difference was statistically significant (P<0.05); there was no significant difference between the two groups in other indicators (P>0.05).
The two types of lumbar brucellosis treatment are safe and effective, and the clinical effect of endoscopic surgery is outstanding, which is more conducive to the postoperative rehabilitation of patients. It is recommended when conditions permit.
本研究旨在比较内镜下腰椎布鲁氏菌病手术与传统后路病灶清除、植骨、融合及内固定联合药物治疗腰椎布鲁氏菌病的疗效及安全性，总结不同手术方式的优缺点，为临床手术决策提供理论支持。
选取2018年1月至2023年6月在新疆医科大学第六附属医院脊柱外科住院的41例腰椎布鲁氏菌病患者，分为内镜组（A组，n = 15）和开放手术组（B组，n = 26）。记录并分析两组患者的一般资料、手术及相关指标、血液生化及影像学指标，并根据各项评分评估临床恢复情况及并发症。
A组与B组基线资料比较差异无统计学意义，具有可比性；A组术后腰椎VAS评分及血红蛋白指标明显优于B组，差异有统计学意义（P<0.05）；A组手术时间、术中出血量及术后下地时间明显优于B组，差异有统计学意义（P<0.05）；两组其他指标比较差异无统计学意义（P>0.05）。
两种治疗腰椎布鲁氏菌病的方法均安全有效，内镜手术临床效果突出，更有利于患者术后康复，条件允许时建议采用。
