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单侧或双侧经皮内镜清创及灌洗治疗腰椎结核

Unilateral or Bilateral Percutaneous Endoscopic Debridement and Lavage Treatment for Lumbar Spinal Tuberculosis.

作者信息

Wu Dongying, Sun Jun, Fan Weimin, Yuan Feng

机构信息

Departments of Orthopedics, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of Orthopedics, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Department of Orthopedics, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

出版信息

World Neurosurg. 2020 Aug;140:e73-e80. doi: 10.1016/j.wneu.2020.04.132. Epub 2020 Apr 25.

DOI:10.1016/j.wneu.2020.04.132
PMID:32344133
Abstract

OBJECTIVE

To compare the clinical outcome between bilateral percutaneous endoscopic debridement and lavage (PEDL) and unilateral PEDL treatment for lumbar spine tuberculosis (LST).

METHODS

A total of 40 patients with LST who underwent either bilateral PEDL (group A) or unilateral PEDL (group B) were reviewed. Perioperative parameters were assessed by operative time, intraoperative fluoroscopy times, and days of postoperative continuous irrigation and vacuum drainage. Clinical outcomes were evaluated in the Oswestry Disability Index (ODI), visual analog scale (VAS), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP). All patients were followed-up for at least 18 months after treatment.

RESULTS

The average operative time and intraoperative fluoroscopy time were increased in group A compared with those in group B. There was no statistical significance between the 2 groups in postoperative continuous irrigation and vacuum drainage days. The ESR and CRP curves in the 2 groups showed a similar trend during 18-month follow-up. The VAS and ODI in the 2 groups significantly decreased 6 and 18 months postsurgery. There was no significant difference in the incidence of complication between the 2 groups.

CONCLUSIONS

Two procedures yielded comparable and satisfactory results. Unilateral PEDL showed shorter operative time and decreased intraoperative fluoroscopy times compared with bilateral PEDL. We suggest the use of unilateral PEDL rather than bilateral PEDL in the treatment of LST.

摘要

目的

比较双侧经皮内镜清创灌洗术(PEDL)与单侧PEDL治疗腰椎结核(LST)的临床疗效。

方法

回顾性分析40例行双侧PEDL(A组)或单侧PEDL(B组)治疗的LST患者。通过手术时间、术中透视次数及术后持续冲洗引流天数评估围手术期参数。采用Oswestry功能障碍指数(ODI)、视觉模拟评分法(VAS)、红细胞沉降率(ESR)及C反应蛋白(CRP)评估临床疗效。所有患者治疗后至少随访18个月。

结果

A组平均手术时间和术中透视时间较B组延长。两组术后持续冲洗引流天数差异无统计学意义。两组ESR和CRP曲线在18个月随访期内呈相似趋势。两组VAS和ODI在术后6个月和18个月时均显著降低。两组并发症发生率差异无统计学意义。

结论

两种手术方法疗效相当且满意。与双侧PEDL相比,单侧PEDL手术时间更短,术中透视次数更少。我们建议在LST治疗中采用单侧PEDL而非双侧PEDL。

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