Chen Chaofan, Wang Xiaolan, Han Xu, Peng Lifan, Zhang Zhiyun
Department of Anorectal, Kunming Municipal Hospital of Traditional Chinese Medicine, The Third Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Front Microbiol. 2025 Apr 8;16:1558490. doi: 10.3389/fmicb.2025.1558490. eCollection 2025.
Despite the growing number of studies on the role of gut microbiota in treating gastrointestinal tumors, the overall research trends in this field remain inadequately characterized.
A bibliometric analysis was conducted using publications retrieved from the Web of Science Core Collection (up to September 30, 2024). Analytical tools including VOSviewer, CiteSpace, and an online bibliometric platform were employed to evaluate trends and hotspots.
Analysis of 1,421 publications revealed significant geographical disparities in research output, with China and the United States leading contributions. Institutionally, the University of Adelaide, Zhejiang University, and Shanghai Jiao Tong University were prominent contributors. Authorship analysis identified Hannah R. Wardill as the most prolific author, while the emerged as a leading journal. Rapidly growing frontiers include "proliferation," "inhibition," "immunotherapy," "drug delivery," and "tumorigenesis."
This study provides a comprehensive overview of research trends and highlights emerging directions, aiming to advance scientific and clinical applications of gut microbiota in gastrointestinal tumor therapy.
尽管关于肠道微生物群在治疗胃肠道肿瘤中的作用的研究数量不断增加，但该领域的整体研究趋势仍未得到充分描述。
使用从科学网核心合集（截至2024年9月30日）检索到的出版物进行文献计量分析。采用包括VOSviewer、CiteSpace和一个在线文献计量平台在内的分析工具来评估趋势和热点。
对1421篇出版物的分析揭示了研究产出的显著地理差异，中国和美国的贡献最大。在机构方面，阿德莱德大学、浙江大学和上海交通大学是主要贡献者。作者分析确定汉娜·R·沃迪尔是最多产的作者，而《 》成为领先期刊。快速发展的前沿领域包括“增殖”“抑制”“免疫疗法”“药物递送”和“肿瘤发生”。
本研究全面概述了研究趋势并突出了新兴方向，旨在推动肠道微生物群在胃肠道肿瘤治疗中的科学和临床应用。
