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链激酶治疗合并肝素相关性血小板减少症的肺栓塞

Streptokinase therapy of pulmonary emboli with heparin-associated thrombocytopenia.

作者信息

Cohen J I, Cooper M R, Greenberg C S

出版信息

Arch Intern Med. 1985 Sep;145(9):1725-6.

PMID:4026502
Abstract

A 59-year-old man developed pulmonary emboli with heparin-associated thrombocytopenia. He was treated simultaneously with intravenous streptokinase and oral warfarin sodium. He responded with complete resolution of perfusion defects on lung scan and did not have any hemorrhagic or thrombotic problems. Although optimal therapy for patients with heparin-associated thrombocytopenia and thrombosis is unknown, fibrinolytic therapy may be useful despite thrombocytopenia, provided appropriate resources are available for careful patient monitoring and transfusion therapy.

摘要

一名59岁男性患肺栓塞并伴有肝素相关性血小板减少症。他同时接受了静脉注射链激酶和口服华法林钠治疗。他的肺部扫描灌注缺损完全消失,且未出现任何出血或血栓形成问题。尽管肝素相关性血小板减少症和血栓形成患者的最佳治疗方法尚不清楚,但在有适当资源用于仔细监测患者和输血治疗的情况下,纤溶治疗可能对血小板减少症患者有用。

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1
Streptokinase therapy of pulmonary emboli with heparin-associated thrombocytopenia.链激酶治疗合并肝素相关性血小板减少症的肺栓塞
Arch Intern Med. 1985 Sep;145(9):1725-6.
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[A case of pulmonary thromboembolism associated with heparin-induced thrombocytopenia].[1例与肝素诱导的血小板减少症相关的肺血栓栓塞病例]
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Thrombolytic therapy in heparin-associated thrombocytopenia with thrombosis.肝素相关性血小板减少症伴血栓形成的溶栓治疗。
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[Arterial embolism and thrombocytopenia during heparin therapy].[肝素治疗期间的动脉栓塞和血小板减少症]
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[A case of pulmonary thromboembolism with heparin-induced thrombocytopenia].[1例合并肝素诱导的血小板减少症的肺血栓栓塞病例]
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Saddle pulmonary embolism in a cancer patient with thrombocytopenia: a treatment dilemma.癌症伴血小板减少症患者的鞍区肺栓塞:治疗困境。
Cardiol Res Pract. 2010 Dec 27;2011:835750. doi: 10.4061/2011/835750.
2
Treatment of the heparin-induced thrombosis-thrombocytopenia syndrome by very low dose streptokinase.极低剂量链激酶治疗肝素诱导的血栓形成-血小板减少综合征
Heart. 1996 Aug;76(2):185-6. doi: 10.1136/hrt.76.2.185.