Johnson R, Charnley J
Clin Orthop Relat Res. 1977 May(124):149-54.
From 1962-73 7,959 total hip replacements were performed by a standardized technique at Wrightington Hospital with 628 (7.89%) non-fatal emboli. Of 603 available for study the effect of different forms of anticoagulant therapy were compared with no therapy. The various antithromboembolic regimens in 295 cases had recurrent emboli in 13 per cent, while without anticoagulant therapy in 308 there were only 3.2 per cent recurrent pulmonary emboli.
1962年至1973年间,赖廷顿医院采用标准化技术进行了7959例全髋关节置换手术,其中628例(7.89%)出现非致命性栓子。在可供研究的603例患者中,将不同形式的抗凝治疗效果与不进行治疗的情况进行了比较。295例采用各种抗血栓栓塞方案的患者中有13%出现复发性栓子,而308例未接受抗凝治疗的患者中只有3.2%出现复发性肺栓子。