Rodrigues Sarah M, Saghafi Afsaneh, Wang Qiao, Shin Sanghyuk S, Dube Sarahjane L, Diestel Annabel, Stevens Robin, Bounds Dawn T
Sue & Bill Gross School of Nursing, University of California, Irvine, California, USA.
Department of Medicine, University of California, Irvine, California, USA.
J Child Adolesc Psychiatr Nurs. 2025 May;38(2):e70017. doi: 10.1111/jcap.70017.
Early initiation of substance use ( 14 years old) constitutes a key target for intervention strategies. This study investigated associations between exposure to adverse childhood experiences (ACEs) and risk for future substance use among young adolescents in the United States (US); the moderating effect of family conflict was also explored.
Mixed-effects modeling was used to analyze self-report data collected from adolescents and parents at baseline and 3-year follow-up (Y3) in the Adolescent Brain Cognitive Development Study (ABCD Study) (Data Release 5.1, 2016-2022, US).
After adjusting for socio-demographic covariates, significant positive associations were found between adolescent ACEs score at baseline (ages 9-10) and risk for future alcohol (b = 0.03, p < 0.001), cigarette/e-cigarette (b = 0.04, p < 0.001), and marijuana use (b = 0.06, p < 0.001) at Y3 (ages 12-13) (n = 10,213 dyads). Family conflict reported at baseline was not found to moderate these associations.
Cumulative ACEs exposure was associated with increased risk for future alcohol, cigarette/e-cigarette, and marijuana use among a national sample of young adolescents. Findings highlight the potential for trauma-informed, developmentally appropriate preventative interventions to mitigate risk for future substance use among adversity-impacted adolescents.
过早开始使用毒品（14岁之前）是干预策略的一个关键目标。本研究调查了美国青少年不良童年经历（ACEs）暴露与未来使用毒品风险之间的关联；同时还探讨了家庭冲突的调节作用。
采用混合效应模型分析青少年大脑认知发展研究（ABCD研究）（2016 - 2022年美国数据版本5.1）中在基线和3年随访（Y3）时从青少年及其父母收集的自我报告数据。
在调整社会人口统计学协变量后，发现基线时（9 - 10岁）青少年的ACEs得分与Y3时（12 - 13岁）未来饮酒（b = 0.03，p < 0.001）、吸烟/吸电子烟（b = 0.04，p < 0.001）和使用大麻（b = 0.06，p < 0.001）的风险之间存在显著正相关（n = 10,213对）。未发现基线时报告的家庭冲突对这些关联有调节作用。
在全国范围内的青少年样本中，累积的ACEs暴露与未来饮酒、吸烟/吸电子烟和使用大麻的风险增加有关。研究结果强调了采用创伤知情、适合发育阶段的预防性干预措施来降低受逆境影响青少年未来使用毒品风险的潜力。
