Bhusal Rachana, Gompo Tulsi Ram, Sugi Tatsuki, Asada Masahito, Pandey Kishor
Central Department of Zoology, Institute of Science and Technology, Tribhuvan University, Kathmandu 44601, Nepal.
Central Veterinary Laboratory, Kathmandu 44600, Nepal.
Vet Sci. 2025 Mar 3;12(3):238. doi: 10.3390/vetsci12030238.
Canine demodicosis is a contagious skin disease caused by the over-proliferation of mites in the host's hair follicles. This study examines the prevalence, clinical signs, and hematological changes associated with demodicosis in street dogs of Rupandehi, Nepal. Between August 2023 and January 2024, 100 skin scrapings were collected from each street dog presenting dermatological symptoms. The samples, treated with 10% KOH and microscopically examined, revealed a 21% positivity rate for demodicosis, with all cases involving . The infection predominantly affected young puppies (37.5%), females (21.6%), mixed breeds (33.3%), and dogs with above-ideal body conditions (25%). There was no significant association between infection and variables such as age, gender, breed, or nutritional status. Clinically, all affected dogs exhibited alopecia, primarily on the legs. Hematological assessments indicated significant increases in neutrophils and eosinophils and a notable decrease in mean corpuscular hemoglobin concentration and lymphocytes among infected dogs ( < 0.05). This study underscores the importance of vigilant monitoring and comprehensive diagnostic practices in effectively managing and treating canine demodicosis, especially in street dogs.
犬蠕形螨病是一种由宿主毛囊内螨虫过度增殖引起的传染性皮肤病。本研究调查了尼泊尔鲁潘德希流浪狗中蠕形螨病的患病率、临床症状和血液学变化。在2023年8月至2024年1月期间，从每只出现皮肤病症状的流浪狗身上采集了100份皮肤刮片。样本经10%氢氧化钾处理后进行显微镜检查，结果显示蠕形螨病的阳性率为21%，所有病例均涉及……。感染主要影响幼犬（37.5%）、雌性犬（21.6%）、混种犬（33.3%）以及身体状况高于理想水平的犬（25%）。感染与年龄、性别、品种或营养状况等变量之间无显著关联。临床上，所有患病犬均出现脱毛，主要集中在腿部。血液学评估表明，感染犬的中性粒细胞和嗜酸性粒细胞显著增加，平均红细胞血红蛋白浓度和淋巴细胞显著减少（<0.05）。本研究强调了在有效管理和治疗犬蠕形螨病，尤其是流浪狗的蠕形螨病时，进行 vigilant monitoring和全面诊断的重要性。 （原文中“with all cases involving.”部分缺失信息未完整翻译）
