Vu Thinh Toan, Johnson Glen, Fleary Sasha, Nguyen Van Thi, Ngo Victoria Khanh
Department of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, New York, USA.
Department of Environmental, Occupational and Geospatial Health Sciences, CUNY Graduate School of Public Health and Health Policy, New York, USA.
Sci Rep. 2025 Apr 23;15(1):14078. doi: 10.1038/s41598-025-96409-5.
This study assessed the severity of mental health concerns, including depression and anxiety, and identified its association with psychosocial and caregiving factors. A cross-sectional study involved 213 family caregivers of lung cancer patients was conducted between June 2023 and August 2024 at a general provincial hospital in Northern Vietnam. Mental health concerns, caregiving challenges (burden, preparedness, and readiness for surrogate decision-making) and psychosocial factors (quality of life and social support) were measured. Modified Poisson regression examined associations between these factors with mental health concerns. Approximately 37% screened positive for mental health concerns, with 29.1% and 27.2% experiencing mild-to-severe depression and anxiety, respectively. Factors positively associated with mild-to-severe depression included being female (Prevalence ratio [PR] = 1.79, 95%CI: 1.07, 3.01), higher caregiving burden (PR = 1.06, 95%CI: 1.04, 1.08) and better caregiving preparedness (PR = 1.34, 95%CI: 1.02, 1.75). Similarly, caregiving burden (PR = 1.05, 95%CI: 1.02, 1.07) was positively associated with mild-to-severe anxiety. Conversely, better quality of life was negatively associated with both mild-to-severe depression (PR = 0.97, 95%CI: 0.95, 0.99) and anxiety (PR = 0.96, 95%CI: 0.94, 0.98). Only social support from friends (PR = 0.87, 95%CI: 0.77, 0.98) was negatively associated with mild-to-severe anxiety. No association was observed between readiness for surrogate decision-making and either mild-to-severe depression or anxiety. This study underscores the significant prevalence of mental health concerns, with one in ten family caregivers meeting the threshold for mental health treatment. The findings advocate for routine mental health screening to enable early identification and intervention. Promoting well-being and bolstering social connections is a critical strategy to mitigate mental health concerns.
本研究评估了包括抑郁和焦虑在内的心理健康问题的严重程度，并确定了其与心理社会因素和照护因素的关联。2023年6月至2024年8月期间，在越南北部的一家省级综合医院对213名肺癌患者的家庭照护者进行了一项横断面研究。测量了心理健康问题、照护挑战（负担、准备情况以及代理决策的准备程度）和心理社会因素（生活质量和社会支持）。采用修正泊松回归分析这些因素与心理健康问题之间的关联。约37%的人心理健康问题筛查呈阳性，分别有29.1%和27.2%的人经历了轻度至重度抑郁和焦虑。与轻度至重度抑郁呈正相关的因素包括女性（患病率比[PR]=1.79，95%置信区间：1.07，3.01）、更高的照护负担（PR=1.06，95%置信区间：1.04，1.08）和更好的照护准备情况（PR=1.34，95%置信区间：1.02，1.75）。同样，照护负担（PR=1.05，95%置信区间：1.02，1.）与轻度至重度焦虑呈正相关。相反，更好的生活质量与轻度至重度抑郁（PR=0.97，95%置信区间：0.95，0.99）和焦虑（PR=0.96，95%置信区间：0.94，0.98）均呈负相关。只有来自朋友的社会支持（PR=0.87，95%置信区间：0.77，0.98）与轻度至重度焦虑呈负相关。未观察到代理决策准备程度与轻度至重度抑郁或焦虑之间存在关联。本研究强调了心理健康问题的显著普遍性，十分之一的家庭照护者达到了心理健康治疗的阈值。研究结果主张进行常规心理健康筛查，以便早期识别和干预。促进幸福感和加强社会联系是减轻心理健康问题的关键策略。
