Farid Awais, Han Wei, Kwan Joseph K C, Yeung King Lun
Division of Environment and Sustainability, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR.
Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR.
Antimicrob Resist Infect Control. 2025 Apr 23;14(1):36. doi: 10.1186/s13756-025-01555-0.
This study aims to assess the bactericidal efficacy of Multilevel Antimicrobial Polymer (MAP-1) on standard bedsheets in Long-term care facility (LTCF). The research quantifies total viable bacteria and MRSA counts and evaluates the percentage difference between treated and control bedding material over a one-week period.
A double-blind interventional, double cross-over study.
Haven of Hope Woo Ping Care and Attention Home in Sai Kung, Hong Kong.
Over an 8-week period, bedding materials from residents' rooms were sampled, totalling 288 samples from 96 bedsheets, with half treated with MAP-1 and the remaining serving as controls. MAP-1, developed at The Hong Kong University of Science and Technology, incorporates USFDA and USEPA-approved polymers. Sampling procedures adhered to standardized protocols, and bacterial counts were determined using culture methods. Data analysis employed t-tests and ANOVA to compare microbial loads between the control and treatment groups, with statistical significance set at p < 0.05.
The study revealed a significant reduction in total viable bacteria and MRSA counts on bedsheets treated with MAP-1. Noteworthy reductions of 80.37% for total bacteria and 87.31% for MRSA at the end of seven-day use, in the intervention group compared to the control. These reductions were statistically significant across all four observation periods and among both male and female residents.
The study establishes the bactericidal efficacy of MAP-1 on standard bedsheets, showcasing its potential in diminishing total bacterial counts and MRSA contamination. These results hold promise for enhancing infection control practices and promoting improved sanitary conditions within healthcare settings.
本研究旨在评估多级抗菌聚合物(MAP-1)对长期护理机构(LTCF)标准床单的杀菌效果。该研究对总活菌数和耐甲氧西林金黄色葡萄球菌(MRSA)数量进行了量化,并评估了经过处理的床单与对照床单材料在一周时间内的百分比差异。
一项双盲干预、双交叉研究。
香港西贡的灵实胡平护理安老院。
在8周的时间里,对居民房间的床单材料进行采样,共采集了来自96张床单的288个样本,其中一半用MAP-1处理,其余作为对照。MAP-1由香港科技大学研发,包含美国食品药品监督管理局(USFDA)和美国环境保护局(USEPA)批准的聚合物。采样程序遵循标准化方案,并使用培养方法确定细菌数量。数据分析采用t检验和方差分析(ANOVA)来比较对照组和治疗组之间的微生物负荷,统计学显著性设定为p < 0.05。
研究表明,用MAP-1处理的床单上的总活菌数和MRSA数量显著减少。与对照组相比,干预组在使用七天结束时,总细菌数显著减少80.37%,MRSA减少87.31%。在所有四个观察期以及男性和女性居民中,这些减少均具有统计学显著性。
该研究证实了MAP-1对标准床单的杀菌效果,展示了其在减少总细菌数和MRSA污染方面的潜力。这些结果有望加强感染控制措施,并改善医疗机构内的卫生条件。