芬氟拉明会延迟固体食物的胃排空。
Fenfluramine delays gastric emptying of solid food.
作者信息
Horowitz M, Collins P J, Tuckwell V, Vernon-Roberts J, Shearman D J
出版信息
Br J Clin Pharmacol. 1985 Jun;19(6):849-51. doi: 10.1111/j.1365-2125.1985.tb02728.x.
Abstract
The effect of a single dose of (+/-)-fenfluramine hydrochloride (40 mg) on gastric emptying of a mixed solid and liquid meal was assessed with a dual isotope scintigraphic technique in eight obese patients. Fenfluramine significantly delayed gastric emptying of solid food (approximately a 15% reduction in the solid linear emptying rate), but had no effect on gastric emptying of liquid.
摘要
采用双同位素闪烁扫描技术，在8名肥胖患者中评估了单剂量盐酸芬氟拉明（±40mg）对混合固体和液体餐胃排空的影响。芬氟拉明显著延迟了固体食物的胃排空（固体线性排空率降低约15%），但对液体的胃排空没有影响。
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