Kim Juhyung, Lorenzo Armando, Rivera Kay Chua, Cheng Alan, Cunningham Jessie, Santos Joana Dos, Sy William Alexander, Rickard Mandy, Kim Jin Kyu, Chua Michael Erlano
Department of Medicine, University of Melbourne, Parkville, VIC, Australia.
University of Toronto, Toronto, ON, Canada.
World J Urol. 2025 Apr 24;43(1):246. doi: 10.1007/s00345-025-05638-w.
Testicular torsion (TT) requires prompt surgical intervention to prevent irreversible damage or orchiectomy. While orchidopexy remains the standard treatment, the tunica vaginalis flap (TVF) has emerged as a novel technique to offer testicular salvage and reduce orchiectomy rates. This systematic review with meta-analysis aims to evaluate the TVF outcomes in TT patients.
This systematic review and meta-analysis adhered to the Cochrane collaborative and PRISMA guidelines. An extensive literature search was conducted up to December 2024. Data extracted included patient characteristics, surgical intervention description, postoperative outcomes, and complications. The ROBINS-I and MINORS tools were utilized to assess the quality of the study.
Eight studies with 293 patients were included. Meta-analysis of three comparative studies revealed that standard orchidopexy had a marginally higher testicular salvage rate than TVF pooled odds ratio of 2.33 (95% CI: 0.95-5.68, p = 0.06). However, this difference was not statistically significant. Testicular salvage rates were notably affected by the duration of ischemia, with prolonged ischemia linked to worse outcomes. Several studies highlighted TVF's effectiveness in preventing orchiectomy by decreasing testicular compartment pressure and postoperative testicular volume retention, maintaining at least 50% of testicular volume. Complications from the TVF procedure were rare. Most studies included in the analysis exhibited a high risk of bias.
TVF may be offered for its potential to preserve testicular volume and prevent orchiectomy, though its effectiveness depends on ischemic duration and procedural standardization. Further research is needed to better assess TVF's role in TT management and refine patient selection criteria.
睾丸扭转(TT)需要及时进行手术干预以防止不可逆转的损害或睾丸切除。虽然睾丸固定术仍然是标准治疗方法,但鞘膜瓣(TVF)已成为一种新的技术,可用于挽救睾丸并降低睾丸切除率。本项带有荟萃分析的系统评价旨在评估TT患者中TVF的治疗效果。
本系统评价和荟萃分析遵循Cochrane协作组和PRISMA指南。截至2024年12月进行了广泛的文献检索。提取的数据包括患者特征、手术干预描述、术后结果和并发症。使用ROBINS-I和MINORS工具评估研究质量。
纳入了八项研究,共293例患者。三项比较研究的荟萃分析显示,标准睾丸固定术的睾丸挽救率略高于TVF,合并优势比为2.33(95%CI:0.95-5.68,p = 0.06)。然而,这种差异无统计学意义。睾丸挽救率受缺血持续时间的显著影响,缺血时间延长与较差的结果相关。多项研究强调了TVF通过降低睾丸腔压力和术后睾丸体积保留来预防睾丸切除的有效性,可维持至少50%的睾丸体积。TVF手术的并发症很少见。分析中纳入的大多数研究显示存在较高的偏倚风险。
TVF因其保留睾丸体积和预防睾丸切除的潜力而可被采用,尽管其有效性取决于缺血持续时间和手术标准化。需要进一步研究以更好地评估TVF在TT治疗中的作用并完善患者选择标准。