• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项卫生技术评估的方法学建议:以生物类似药为例的案例研究。

A Methodological Proposal for Health Technology Assessments: A Case Study on Biosimilar Drugs.

作者信息

Dimmito Marilisa Pia, Marinelli Lisa, Toto Eleonora Chiara, Di Biase Giuseppe, Cacciatore Ivana, Toto Pierpaolo, Ciulla Michele, Monti Benedetta, Santoleri Fiorenzo, Costantini Alberto, Di Stefano Antonio

机构信息

Department of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy;

ASL Benevento U.O.C. Assistenza Farmaceutica, Via Trieste e Trento, 82100 Benevento, Italy;

出版信息

J Mark Access Health Policy. 2025 Mar 31;13(2):12. doi: 10.3390/jmahp13020012. eCollection 2025 Jun.

DOI:10.3390/jmahp13020012
PMID:40276089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12015889/
Abstract

This work proposes a methodological approach that could be useful in multidisciplinary health technology assessments (HTAs). Mathematical models based on real data were used to make predictions for the initial price and actual cost of three classes of biological drugs. Through a comparison of real data, with the data derived through this approach, degree coefficients were formulated to rank the negotiating capabilities of Italian regions. The proposed method could represent a valid means of support for healthcare decisionmakers in planning and reducing pharmaceutical spending, evaluating data, and finding uses for particular medical technologies. This study could be a useful tool for achieving the objectives of HTAs, providing a means of analysis that can be adapted to any data, which may be useful for rationalizing the use of health technologies, reducing waste, and optimally reallocating resources.

摘要

这项工作提出了一种方法,该方法可能对多学科卫生技术评估(HTA)有用。基于真实数据的数学模型被用于预测三类生物药物的初始价格和实际成本。通过将真实数据与通过该方法得出的数据进行比较,制定了程度系数以对意大利各地区的谈判能力进行排名。所提出的方法可以成为医疗保健决策者在规划和减少药品支出、评估数据以及寻找特定医疗技术用途方面的有效支持手段。这项研究可能是实现卫生技术评估目标的有用工具,提供一种可适用于任何数据的分析方法,这对于合理使用卫生技术、减少浪费以及优化资源重新分配可能是有用的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/0ec652b423eb/jmahp-13-00012-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/d5c07fd7e09e/jmahp-13-00012-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/24d92dfe06ed/jmahp-13-00012-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/784ffb54d897/jmahp-13-00012-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/178b9437272d/jmahp-13-00012-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/9e20957ec1f8/jmahp-13-00012-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/f29a97b81dc7/jmahp-13-00012-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/0020fc0b8fdd/jmahp-13-00012-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/2ccc4c9ad257/jmahp-13-00012-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/3c5016e47874/jmahp-13-00012-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/0ec652b423eb/jmahp-13-00012-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/d5c07fd7e09e/jmahp-13-00012-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/24d92dfe06ed/jmahp-13-00012-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/784ffb54d897/jmahp-13-00012-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/178b9437272d/jmahp-13-00012-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/9e20957ec1f8/jmahp-13-00012-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/f29a97b81dc7/jmahp-13-00012-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/0020fc0b8fdd/jmahp-13-00012-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/2ccc4c9ad257/jmahp-13-00012-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/3c5016e47874/jmahp-13-00012-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e83/12015889/0ec652b423eb/jmahp-13-00012-g010.jpg

相似文献

1
A Methodological Proposal for Health Technology Assessments: A Case Study on Biosimilar Drugs.一项卫生技术评估的方法学建议:以生物类似药为例的案例研究。
J Mark Access Health Policy. 2025 Mar 31;13(2):12. doi: 10.3390/jmahp13020012. eCollection 2025 Jun.
2
Mapping Health Technology Assessment Agency Approaches for Biosimilar Value Assessment: An ISPOR Special Interest Group Report.评估生物类似药价值的方法:卫生技术评估机构的方法概述——ISPOR 特别兴趣小组报告
Value Health. 2024 May;27(5):543-551. doi: 10.1016/j.jval.2024.01.018.
3
Health technology assessment of biosimilars worldwide: a scoping review.全球生物类似药的卫生技术评估:一项范围综述
Health Res Policy Syst. 2020 Aug 26;18(1):95. doi: 10.1186/s12961-020-00611-y.
4
Budget Impact Analysis of Biosimilar Products in Spain in the Period 2009-2019.2009 - 2019年西班牙生物类似药产品的预算影响分析
Pharmaceuticals (Basel). 2021 Apr 9;14(4):348. doi: 10.3390/ph14040348.
5
Association of Generic Competition With Price Decreases in Physician-Administered Drugs and Estimated Price Decreases for Biosimilar Competition.医生管理药物的仿制药竞争与价格下降的关联,以及预计生物类似药竞争带来的价格下降。
JAMA Netw Open. 2021 Nov 1;4(11):e2133451. doi: 10.1001/jamanetworkopen.2021.33451.
6
Impact of Value-Driven Healthcare Strategies for Biosimilar Adoption: The Singapore Story.价值驱动型医疗保健策略对生物类似药采用的影响:新加坡的故事
Pharmacoecon Open. 2024 Sep;8(5):679-688. doi: 10.1007/s41669-024-00491-w. Epub 2024 Jul 23.
7
Infliximab Pricing in International Economic Evaluations in Inflammatory Bowel Disease to Inform Biologic and Biosimilar Access Policies: A Systematic Review.英夫利昔单抗在炎症性肠病国际经济评估中的定价以指导生物制剂和生物类似药的准入政策:一项系统评价
MDM Policy Pract. 2023 Feb 24;8(1):23814683231156433. doi: 10.1177/23814683231156433. eCollection 2023 Jan-Jun.
8
Examining Opportunities to Increase Savings From Medicare Price Negotiations.审视增加 Medicare 价格谈判节省机会。
JAMA Intern Med. 2023 Jun 1;183(6):581-588. doi: 10.1001/jamainternmed.2023.0763.
9
Biosimilar Cost Savings in the United States: Initial Experience and Future Potential.美国生物类似药的成本节约:初步经验与未来潜力
Rand Health Q. 2018 Mar 30;7(4):3. eCollection 2018 Mar.
10
Health Technology Assessments in Radiology in Germany: Lack of Demand, Lack of Supply.德国放射学领域的卫生技术评估:需求不足,供给不足。
Rofo. 2019 Jul;191(7):635-642. doi: 10.1055/a-0838-6253. Epub 2019 Feb 14.

本文引用的文献

1
The added value of applying a disinvestment approach to the process of health technology assessment in Italy.应用去投资方法于意大利卫生技术评估过程的附加值。
Int J Technol Assess Health Care. 2023 Mar 2;39(1):e17. doi: 10.1017/S0266462323000107.
2
Cost-minimization analysis to support the HTA of Radiofrequency Echographic Multi Spectrometry (REMS) in the diagnosis of osteoporosis.成本最小化分析,以支持射频超声多光谱测定法(REMS)在骨质疏松症诊断中的卫生技术评估。
Glob Reg Health Technol Assess. 2023 Feb 6;10:1-11. doi: 10.33393/grhta.2023.2492. eCollection 2023 Jan-Dec.
3
Healthcare Systems across Europe and the US: The Managed Entry Agreements Experience.
欧洲和美国的医疗保健系统:有条件准入协议的经验
Healthcare (Basel). 2023 Feb 3;11(3):447. doi: 10.3390/healthcare11030447.
4
Health technology assessment and economic evaluation: Is it applicable for the traditional medicine?卫生技术评估与经济评估:它适用于传统医学吗?
Integr Med Res. 2022 Mar;11(1):100756. doi: 10.1016/j.imr.2021.100756. Epub 2021 Jul 16.
5
The Role of Health Technologies in Multicomponent Primary Care Interventions: Systematic Review.健康技术在多组分初级保健干预中的作用:系统评价。
J Med Internet Res. 2021 Jan 11;23(1):e20195. doi: 10.2196/20195.
6
Disinvestment in healthcare: an overview of HTA agencies and organizations activities at European level.医疗保健领域的撤资:欧洲层面卫生技术评估机构及组织活动概述
BMC Health Serv Res. 2018 Mar 1;18(1):148. doi: 10.1186/s12913-018-2941-0.
7
Using health technology assessment to assess the value of new medicines: results of a systematic review and expert consultation across eight European countries.利用健康技术评估来评估新药的价值:在八个欧洲国家进行的系统评价和专家咨询的结果。
Eur J Health Econ. 2018 Jan;19(1):123-152. doi: 10.1007/s10198-017-0871-0. Epub 2017 Mar 16.
8
Medical technology as a key driver of rising health expenditure: disentangling the relationship.医疗技术作为医疗支出增长的关键驱动因素:理清两者关系。
Clinicoecon Outcomes Res. 2013 May 30;5:223-34. doi: 10.2147/CEOR.S39634. Print 2013.
9
Developing Health Technology Assessment to address health care system needs.制定卫生技术评估以满足医疗保健系统需求。
Health Policy. 2010 Mar;94(3):196-202. doi: 10.1016/j.healthpol.2009.10.002. Epub 2009 Nov 3.
10
Health technology assessment: lessons learned from around the world--an overview.卫生技术评估:来自世界各地的经验教训——概述
Value Health. 2009 Jun;12 Suppl 2:S1-5. doi: 10.1111/j.1524-4733.2009.00550.x.