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Quantitation of Hb a2 with DE-52 microchromatography in whole blood as screening test for beta-thalassemia heterozygotes.

作者信息

Galanello R, Melis M A, Muroni P, Cao A

出版信息

Acta Haematol. 1977;57(1):32-6. doi: 10.1159/000207857.

DOI:10.1159/000207857
PMID:402762
Abstract

HB A2 was assayed by means of DE-52 microchromatography in hemolysates from 285 normal subjects and 223 beta-thalassemia heterozygotes. No overlap was found between both groups. Comparable results were observed analyzing whole blood samples collected in capillary tubes from 550 normal subjects and 295 beta-thalassemia heterozygotes. Our results demonstrate that this technique is useful in a screening program for beta-thalassemia trait.

摘要

相似文献

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Quantitation of Hb a2 with DE-52 microchromatography in whole blood as screening test for beta-thalassemia heterozygotes.
Acta Haematol. 1977;57(1):32-6. doi: 10.1159/000207857.
2
A test tube method for quantitation of hemoglobin A2 using DE 52 cellulose.
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Am J Hum Genet. 1981 Jul;33(4):592-605.
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