Satorre J, Cano J, Reinoso-Suárez F
Brain Res. 1985 Jul 29;339(2):375-7. doi: 10.1016/0006-8993(85)90108-8.
The variations, with aging, of both neuronal and glial populations of the rat LGNd have been studied quantitatively. Our results show a stability of the total number of neurons of the rat LGNd with aging; this, plus the constant increase of the rat LGNd volume throughout rat life, causes the neuronal density to decrease slowly. Our data prove the necessity of determining the total number of neurons, not just neuronal density, in order to find out the actual evolution of the neuronal population with aging. Both glial cell number and density show an increase throughout rat life.
已经对大鼠外侧膝状体核（LGNd）中神经元和神经胶质细胞群体随衰老的变化进行了定量研究。我们的结果表明，大鼠LGNd中神经元的总数随衰老保持稳定；这一点，再加上大鼠整个生命过程中LGNd体积的持续增加，导致神经元密度缓慢下降。我们的数据证明，为了弄清楚神经元群体随衰老的实际演变情况，确定神经元的总数而非仅仅是神经元密度是必要的。在大鼠的整个生命过程中，神经胶质细胞的数量和密度均呈现增加趋势。
