Iyengar B
Acta Haematol. 1977;57(2):81-6. doi: 10.1159/000207863.
Hemopoietic activity in the spleen is caused by the proliferation of the RE cells of the red pulp, lining the sinusoids and the endothelial cells lining the venous channels and their vasa vasora. The RE cells of the marginal zone do not contribute. As the cells involved line blood spaces, and the immature cells are washed into the circulation hemopoiesis appears to be intravascular. Different agents produce different effect: copper sulphate an early proliferation of both the red pulp and venous cells, phenylhydrazine a red pulp proliferation and antiserum a high venous endothelial activity.
脾脏中的造血活动是由红髓的网状内皮细胞（RE细胞）增殖引起的，这些细胞衬于血窦以及静脉通道及其血管滋养管的内皮细胞。边缘区的RE细胞不参与。由于涉及的细胞衬于血腔，未成熟细胞被冲入循环，因此造血似乎是在血管内进行的。不同的药物产生不同的效果：硫酸铜可使红髓和静脉细胞早期增殖，苯肼可使红髓增殖，抗血清可使静脉内皮细胞高度活跃。
