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基于MoS的纳米复合材料在癌症治疗中的结构、光学和热性能比较。

Comparison of structural, optical, and thermal properties in MoS based nanocomposites into cancer therapy.

作者信息

Abareshi Afsaneh, Shahidi Mohammad Mahdi, Salehi Nasrin

机构信息

Department of Physics, Shahid Beheshti University, Evin, Tehran, Iran.

UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology College of Graduates Studies, University of South Africa, Muckleneuk Ridge, Pretoria, 392, South Africa.

出版信息

J Mater Sci Mater Med. 2025 Apr 25;36(1):33. doi: 10.1007/s10856-025-06883-6.

DOI:10.1007/s10856-025-06883-6
PMID:40278959
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12031748/
Abstract

The objective of the present study is to evaluate the potential of novel molybdenum disulfide (MoS)-based nanocomposites for photothermal therapy. For this purpose, MoS-CuS (MoCS) and MoS-AuNR (MoAu) nanocomposites were synthesized by physically mixing MoS suspensions with CuS and AuNRs, respectively. The structural and optical properties of these nanocomposites were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectroscopy, and Fourier transform infrared (FTIR) spectroscopy. The photothermal performance of the nanocomposites was assessed under near-infrared (NIR) radiation at a power density of 1 W/cm for 10 min. The results demonstrated that both MoCS and MoAu nanocomposites exhibited enhanced photothermal heating compared to their individual components. Furthermore, the MoAu nanocomposite generated higher photothermal heat than the MoCS nanocomposite. These findings suggest that the MoCS and MoAu nanocomposites have strong potential as novel photothermal agents for cancer therapy.

摘要

本研究的目的是评估新型二硫化钼(MoS)基纳米复合材料用于光热治疗的潜力。为此,分别通过将MoS悬浮液与CuS和金纳米棒(AuNRs)物理混合来合成MoS-CuS(MoCS)和MoS-AuNR(MoAu)纳米复合材料。使用X射线衍射(XRD)、透射电子显微镜(TEM)、紫外可见(UV-Vis)光谱和傅里叶变换红外(FTIR)光谱对这些纳米复合材料的结构和光学性质进行了表征。在功率密度为1 W/cm的近红外(NIR)辐射下照射10 min,评估了纳米复合材料的光热性能。结果表明,与它们各自的组分相比,MoCS和MoAu纳米复合材料均表现出增强的光热加热效果。此外,MoAu纳米复合材料产生的光热比MoCS纳米复合材料更高。这些发现表明,MoCS和MoAu纳米复合材料作为用于癌症治疗的新型光热剂具有很大的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/538c16f51e70/10856_2025_6883_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/e47a4db9b009/10856_2025_6883_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/cef98db685a2/10856_2025_6883_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/6fdb97e39cec/10856_2025_6883_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/5d0a61940613/10856_2025_6883_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/d94e7d139b6b/10856_2025_6883_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/34f9afbdde10/10856_2025_6883_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/22362b55927d/10856_2025_6883_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/1676908796a5/10856_2025_6883_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/538c16f51e70/10856_2025_6883_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/e47a4db9b009/10856_2025_6883_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/cef98db685a2/10856_2025_6883_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/6fdb97e39cec/10856_2025_6883_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/5d0a61940613/10856_2025_6883_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/d94e7d139b6b/10856_2025_6883_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/34f9afbdde10/10856_2025_6883_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/22362b55927d/10856_2025_6883_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/1676908796a5/10856_2025_6883_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/faa6/12031748/538c16f51e70/10856_2025_6883_Fig9_HTML.jpg

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本文引用的文献

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