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隐匿性前庭神经鞘瘤:一系列不寻常病例

Unmasking vestibular schwannoma: A series of unusual cases.

作者信息

Haider Nataly, Radi Qais, Ahmad Solaf, Mohsen Samer

机构信息

Faculty of Medicine, Damascus University, Damascus, Syria.

Faculty of Medicine, Damascus University, Damascus, Syria.

出版信息

Int J Surg Case Rep. 2025 Jun;131:111291. doi: 10.1016/j.ijscr.2025.111291. Epub 2025 Apr 12.

DOI:10.1016/j.ijscr.2025.111291
PMID:40279996
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12060521/
Abstract

INTRODUCTION

Vestibular schwannoma (VS) is a benign, slow-growing tumor that accounts for 80-90 % of cerebellopontine angle (CPA) tumors. While classic symptoms like hearing loss, tinnitus, and vertigo are well-recognized, atypical presentations can delay diagnosis.

CASE PRESENTATION

We present four unusual cases of VS. The first patient, a 33-year-old woman, initially presented with transient tinnitus and later developed peripheral vertigo. The second case involved a 52-year-old man with sudden hearing loss, vertigo, and aural fullness. The third case was a 17-year-old female with unilateral auditory neuropathy. The fourth patient, a 39-year-old woman, presented with intermittent tinnitus, balance disturbances, and facial stiffness.

DISCUSSION

Detailed history, physical examination, and audiological evaluation are crucial for identifying patients at risk for vestibular schwannoma, especially with atypical audiological findings, to avoid misdiagnosis.

CONCLUSION

This case series emphasizes the significance of considering VS as a differential diagnosis for atypical symptoms. Early recognition and proper practice can lead to optimal outcomes for patients and contribute valuable insights to the scientific field by broadening the understanding of the diverse spectrum of VS symptoms.

摘要

引言

前庭神经鞘瘤(VS)是一种良性、生长缓慢的肿瘤,占桥小脑角(CPA)肿瘤的80 - 90%。虽然听力损失、耳鸣和眩晕等典型症状已广为人知,但非典型表现可能会延迟诊断。

病例报告

我们介绍4例不寻常的前庭神经鞘瘤病例。首例患者为一名33岁女性,最初表现为短暂性耳鸣,随后出现周围性眩晕。第二例是一名52岁男性,突发听力损失、眩晕和耳闷胀感。第三例是一名17岁女性,患有单侧听觉神经病。第四例患者为一名39岁女性,表现为间歇性耳鸣、平衡障碍和面部僵硬。

讨论

详细的病史、体格检查和听力学评估对于识别有前庭神经鞘瘤风险的患者至关重要,尤其是对于有非典型听力学表现的患者,以避免误诊。

结论

本病例系列强调了将前庭神经鞘瘤作为非典型症状鉴别诊断的重要性。早期识别和正确处理可为患者带来最佳治疗效果,并通过拓宽对前庭神经鞘瘤症状多样谱的理解,为科学领域提供有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/ae310b114571/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/1eae88162f37/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/34eb8bb7d859/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/3ceeba2074dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/ae310b114571/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/1eae88162f37/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/34eb8bb7d859/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/3ceeba2074dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d0f/12060521/ae310b114571/gr4.jpg

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本文引用的文献

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Preferred Reporting Of Case Series in Surgery (PROCESS) 2023 guidelines.外科手术病例系列报告首选方法(PROCESS)2023 指南。
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Multiple Audiometric Analysis in the Screening of Vestibular Schwannoma.前庭神经鞘瘤筛查中的多项听力测定分析
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Neuromonitoring of the cochlear nerve during vestibular schwannoma resection and simultaneous cochlear implantation.前庭神经鞘瘤切除术中同时进行耳蜗神经监测和耳蜗植入。
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The influences of porus acusticus internus on ethnicity and importance in preoperative and intraoperative approaches.内听道孔对种族的影响及在术前和术中入路的重要性。
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