Shameem Yasmin, Kraft Katharina, Joseph Anjana, Johnson Jo-Anne
Dermatology, Mid and South Essex NHS Foundation Trust, Basildon, UK.
Dermatology, Mid and South Essex NHS Foundation Trust, Basildon, UK
BMJ Case Rep. 2025 Apr 24;18(4):e265426. doi: 10.1136/bcr-2025-265426.
Herpes zoster (HZ) in infancy is considered rare as both primary infection with varicella-zoster virus (VZV) and the reactivation of latent VZV would have to occur in the first year of life. We report a case of HZ, in an otherwise immunocompetent young infant, with a previous history of neonatal varicella. This case highlights the clinical presentation, management strategies and potential complications of infantile HZ, with a discussion of relevant literature. We advocate for a high index of clinical suspicion for infants who present with crusted lesions limited to one or two dermatomes to facilitate timely intervention, as well as long-term follow-up to improve clinical outcomes.
婴儿期带状疱疹(HZ)被认为较为罕见,因为水痘 - 带状疱疹病毒(VZV)的原发性感染和潜伏VZV的再激活都必须发生在生命的第一年。我们报告了一例HZ病例,患儿为一名免疫功能正常的幼儿,既往有新生儿水痘病史。本病例突出了婴儿期HZ的临床表现、管理策略和潜在并发症,并对相关文献进行了讨论。我们主张对于出现局限于一两个皮节的结痂性皮损的婴儿保持高度的临床怀疑,以便及时干预,并进行长期随访以改善临床结局。