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伴有皮肤播散的带状疱疹:儿童罕见的不常见病理表现。

Herpes zoster with cutaneous dissemination: a rare presentation of an uncommon pathology in children.

作者信息

Faria Catarina, Antunes Ana, Antunes Henedina, Carvalho Susana

机构信息

Department of Pediatrics, Hospital de Braga, Braga, Portugal.

Life and Health Sciences Research Institute (ICVS), School of Health Sciences; ICVS/3B's-PT Government Associate Laboratory, Universidade do Minho, Braga/Guimarães, Portugal.

出版信息

BMJ Case Rep. 2018 Jun 12;2018:bcr-2018-225355. doi: 10.1136/bcr-2018-225355.

DOI:10.1136/bcr-2018-225355
PMID:29895579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6011528/
Abstract

Herpes zoster, caused by varicella zoster virus (VZV) reactivation, affects mainly the adult population, although it can occur in children. This happens when primary infection (varicella) has occurred at a very young age or in immunocompromised patients. Complications are rare in healthy individuals. They include VZV cutaneous dissemination, which affects 2%-10% of immunocompromised patients.We present a previously healthy child, with history of varicella during her first month of life, which presented at age 8 with a severe case of herpes zoster, complicated with cutaneous dissemination. Immunity study was unremarkable. Causes, management and follow-up are discussed.

摘要

带状疱疹由水痘-带状疱疹病毒(VZV)再激活引起,主要影响成人,但也可能发生在儿童身上。这种情况发生在极幼年时发生原发性感染(水痘)或免疫功能低下的患者身上。健康个体中并发症很少见。并发症包括VZV皮肤播散,影响2%-10%的免疫功能低下患者。我们报告一名既往健康的儿童,在出生后第一个月患过水痘,8岁时出现严重的带状疱疹病例,并伴有皮肤播散。免疫研究无异常。本文讨论了病因、治疗和随访情况。

相似文献

1
Herpes zoster with cutaneous dissemination: a rare presentation of an uncommon pathology in children.伴有皮肤播散的带状疱疹:儿童罕见的不常见病理表现。
BMJ Case Rep. 2018 Jun 12;2018:bcr-2018-225355. doi: 10.1136/bcr-2018-225355.
2
Herpes zoster and meningitis in an immunocompetent child: a case report.一名免疫功能正常儿童的带状疱疹与脑膜炎:病例报告
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Antiviral therapy for varicella and herpes zoster.水痘和带状疱疹的抗病毒治疗。
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Pediatr Rheumatol Online J. 2016 Jun 2;14(1):34. doi: 10.1186/s12969-016-0095-3.

本文引用的文献

1
Disseminated herpes zoster ophthalmicus in an immunocompetent 8-year old boy.一名免疫功能正常的8岁男孩患播散性眼带状疱疹。
Clin Pract. 2013 May 20;3(2):e16. doi: 10.4081/cp.2013.e16. eCollection 2013 Aug 2.
2
Examination of links between herpes zoster incidence and childhood varicella vaccination.带状疱疹发病率与儿童水痘疫苗接种之间关联的研究
Ann Intern Med. 2013 Dec 3;159(11):739-45. doi: 10.7326/0003-4819-159-11-201312030-00006.
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Childhood herpes zoster: a clustering of ten cases.儿童带状疱疹:10例病例聚集性报告
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4
Immunocompetent children account for the majority of complications in childhood herpes zoster.免疫功能正常的儿童占儿童带状疱疹并发症的大多数。
J Infect Dis. 2007 Nov 15;196(10):1455-8. doi: 10.1086/522631.
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Recommendations for the management of herpes zoster.带状疱疹管理建议。
Clin Infect Dis. 2007 Jan 1;44 Suppl 1:S1-26. doi: 10.1086/510206.
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Herpes zoster with dissemination.播散性带状疱疹
Indian Pediatr. 2006 Apr;43(4):353-6.
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Herpes zoster in the first year of life following postnatal exposure to varicella-zoster virus: four case reports and a review of infantile herpes zoster.出生后接触水痘-带状疱疹病毒后第一年发生的带状疱疹:4例病例报告及婴儿带状疱疹综述
Arch Dermatol. 2004 Oct;140(10):1268-72. doi: 10.1001/archderm.140.10.1268.
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Varicella, herpes zoster and dissemination.水痘、带状疱疹及播散
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9
Exposure to varicella boosts immunity to herpes-zoster: implications for mass vaccination against chickenpox.接触水痘可增强对带状疱疹的免疫力:对水痘大规模疫苗接种的启示。
Vaccine. 2002 Jun 7;20(19-20):2500-7. doi: 10.1016/s0264-410x(02)00180-9.