Fu Yanqing, Kang Shiliang, Zhou Gangjie, Huang Xinxiang, Tan Linling, Gao Chengwei, Dai Shixun, Lin Changgui
Laboratory of Infrared Materials and Devices, The Research Institute of Advanced Technologies, Ningbo University, Ningbo, 315211, China.
Zhejiang Key Laboratory of Advanced Optical Functional Materials and Devices, Ningbo, 315211, China.
Light Sci Appl. 2025 Apr 25;14(1):173. doi: 10.1038/s41377-025-01840-y.
Improvements to body-surface physiological monitoring ability including real-time, accuracy and integration, are essential to meet the expansive demands for personal healthcare. As part of this, simultaneous monitoring of sweat metabolites and body temperature offers an exciting path to maximizing diagnostic precision and minimizing morbidity rates. Herein, we report a high-performance biomarker-temperature sensor made of a single AsSeTe chalcogenide glass fiber to monitor physiology evolution on body-surface. The sensor integrates efficient thermal resistance and fiber evanescent wave effects, permitting the independent sensing of temperature and biomarkers with an ultrahigh temperature coefficient of resistance (-5.84% K), rapid temperature response (0.3 s) and excellent IR sensing sensitivity. Moreover, by attaching a fiber to the wrist, we demonstrate simultaneous observation of both sweat metabolite (urea and lactate) and temperature changes during exercise. This illuminating sensing method will provide crucial capabilities in physiological monitoring and pave the way for advanced personalized diagnostic.
提高体表生理监测能力，包括实时性、准确性和集成性，对于满足个人医疗保健不断增长的需求至关重要。作为其中一部分，同时监测汗液代谢物和体温为最大限度提高诊断精度和降低发病率提供了一条令人兴奋的途径。在此，我们报道了一种由单一AsSeTe硫属化物玻璃纤维制成的高性能生物标志物 - 温度传感器，用于监测体表的生理变化。该传感器集成了高效的热阻和光纤倏逝波效应，能够以超高的电阻温度系数（-5.84% K）、快速的温度响应（0.3 秒）和出色的红外传感灵敏度独立传感温度和生物标志物。此外，通过将光纤附着在手腕上，我们展示了在运动过程中同时观察汗液代谢物（尿素和乳酸）和温度变化。这种具有启发性的传感方法将在生理监测中提供关键能力，并为先进的个性化诊断铺平道路。
