Moro Marianna, de Gioia Alessia, D'Amario Giulia, Napoli Valentina, Venezia Ilaria, Mirra Federica, D'Ambrosio Martina, Venditti Romina, Sestito Simona, De Stefano Andrea, Di Domenico Sara, Romeo Domenico, Mercuri Eugenio, Brogna Claudia
Pediatric Neurology Unit, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Psychologist and Psychoterapist, Piazza Attilio Omodei Zorini 11, 00166 Rome, Italy.
Medicina (Kaunas). 2025 Mar 31;61(4):637. doi: 10.3390/medicina61040637.
is a form of social withdrawal lasting more than 6 months with significant associated functional impairment. To date, numerous studies confirm the presence of this condition not only in Japan, where it was first described, but also globally abroad. This is an underestimated clinical condition, and it is emerging especially in adolescents and young adults, representing an increasing management problem for families and society. Prevalence ranges from 1.1% to 6.7%. can be associated with other neurodevelopmental disorders, such as Autism Spectrum Disorder (ASD). Indeed, ASD and share numerous characteristics confirmed by functional neuroimaging studies that have highlighted in both conditions the presence of alterations in cerebral regions related to social functioning. We present a case report regarding the history of a 14-year-old girl with characteristics compatible with ASD and . At present, there are no specific treatments approved for in ASD patients. Further studies are necessary to understand the link between the two conditions, the boundary, and possible overlap.
是一种持续超过6个月的社交退缩形式,伴有明显的相关功能损害。迄今为止,众多研究证实,这种病症不仅在首次描述它的日本存在,在全球其他国家也存在。这是一种被低估的临床病症,尤其在青少年和年轻人中出现,给家庭和社会带来越来越多的管理问题。患病率在1.1%至6.7%之间。它可能与其他神经发育障碍有关,如自闭症谱系障碍(ASD)。事实上,ASD和该病症具有许多功能神经影像学研究所证实的共同特征,这些研究在两种病症中都突出了与社交功能相关的脑区存在改变。我们呈现了一例关于一名14岁女孩的病例报告,其特征与ASD和该病症相符。目前,尚无针对ASD患者中该病症的特定批准治疗方法。需要进一步研究以了解这两种病症之间的联系、界限以及可能的重叠情况。