Dalah Entesar Z, Al Mazrouei Najlaa K, Al Ali Zahra A
Central Diagnostic Imaging Department, Dubai Health, Dubai P.O. Box 2727, United Arab Emirates.
College of Medicine, Mohammed Bin Rashid University, Dubai Health, Dubai P.O. Box 2727, United Arab Emirates.
Life (Basel). 2025 Apr 15;15(4):649. doi: 10.3390/life15040649.
Nuclear medicine (NM) procedures are performed using unsealed radioactive sources that are administered to patients, resulting in both internal and external exposure for patients and staff alike. Optimization is mainly concerned with ensuring the use of the lowest sufficient level of radiation to perform a procedure while maintaining adequate image quality. Diagnostic reference levels (DRLs) have been proven effective in aiding optimization in clinical practice. This dose review aims to establish an inclusive DRL system for the common adult NM procedures performed at Dubai Health. Our defined DRLs will focus on both the administered radiopharmaceuticals and the radiation dose metrics derived from hybrid computed tomography (CT). Dose surveys for 1439 adult nuclear medicine procedures performed over twelve months were collected and retrospectively analyzed. DRLs were obtained for a total of eight scintigraphy procedures, four hybrid positron emission tomography procedures with CT (denoted PET/CT), and five target sites for CT hybrid single-photon emission tomography with CT (denoted as SPECT/CT). Our derived DRLs for the scintigraphy, hybrid SPECT/CT and PET/CT procedures are within the reported national DRLs, except for the CT dose of the hybrid SPECT/CT for the neck, abdomen and chest/abdomen sites and the F PSMA administered activity. A fixed activity dose was administered for a scintigraphy procedure that is weight dependent. This patient dose review serves as a foundational effort aiming to optimize radiation safety and standardize diagnostic practices in NM. Further research is needed to enhance adherence to safety benchmarks.
核医学(NM)程序使用未密封的放射性源进行,这些放射性源被施用于患者,导致患者和工作人员都受到内部和外部辐射。优化主要关注确保在保持足够图像质量的同时,使用最低足够水平的辐射来执行程序。诊断参考水平(DRLs)已被证明在临床实践中有助于优化。本次剂量审查旨在为迪拜健康城进行的常见成人核医学程序建立一个全面的DRL系统。我们定义的DRLs将关注所施用的放射性药物以及从混合计算机断层扫描(CT)得出的辐射剂量指标。收集并回顾性分析了在十二个月内进行的1439例成人核医学程序的剂量调查。总共获得了八种闪烁扫描程序、四种带有CT的混合正电子发射断层扫描程序(称为PET/CT)以及五种带有CT的混合单光子发射断层扫描程序(称为SPECT/CT)的CT剂量的DRLs。我们得出的闪烁扫描、混合SPECT/CT和PET/CT程序的DRLs在已报告的国家DRLs范围内,但颈部、腹部以及胸部/腹部部位的混合SPECT/CT的CT剂量和所施用的F PSMA活度除外。对于一种与体重相关的闪烁扫描程序施用了固定活度剂量。本次患者剂量审查是一项基础性工作,旨在优化核医学中的辐射安全并规范诊断实践。需要进一步研究以加强对安全基准的遵守。