Maritescu Adelina, Pescaru Camelia Corina, Crisan Alexandru Florian, Stoicescu Emil Robert, Oancea Cristian, Iacob Daniela
Doctoral School, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Pulmonary Rehabilitation Center, Clinical Hospital of Infectious Diseases and Pulmonology, "Victor Babes", 300310 Timisoara, Romania.
J Clin Med. 2025 Apr 18;14(8):2807. doi: 10.3390/jcm14082807.
: Cystic fibrosis (CF) is a chronic genetic disease affecting multiple body systems and having a significant impact on mental health and sleep. Patients with CF frequently suffer from anxiety, depression, and sleep disturbances, but non-pharmacological strategies are understudied. Although progressive muscle relaxation (PMR) has recognized benefits, its impact on CF remains insufficiently explored. The study aimed to analyze the effect of integrating PMR into a standard pulmonary rehabilitation (PR) program on mental health, sleep quality, and quality of life in adults with CF. : A total of 22 adult patients with CF were randomly assigned to either the intervention group (PR + PMR) or the control group (PR only). Assessments were performed at baseline, after 21 days of intervention, and at the 48-day follow-up. Outcome measures included the CFQ-R for quality of life, the HADS for mental health, and the PSQI for sleep. : Compared to the control group, participants who practiced PMR experienced significant reductions in anxiety ( = 0.05) and depression ( = 0.02) at the final assessment. A significant improvement in sleep quality was also observed ( < 0.01). No relevant differences were found in pulmonary function or performance on the six-minute walk test. : Integrating PMR into pulmonary rehabilitation programs may be an effective strategy for improving mental health and sleep in patients with CF. Due to its accessibility and ease of implementation, PMR could be adopted as a complementary method in the holistic care of these patients.
囊性纤维化（CF）是一种慢性遗传疾病，会影响多个身体系统，并对心理健康和睡眠产生重大影响。CF患者经常遭受焦虑、抑郁和睡眠障碍，但非药物治疗策略的研究较少。尽管渐进性肌肉松弛（PMR）已被认可具有益处，但其对CF的影响仍未得到充分探索。该研究旨在分析将PMR纳入标准肺康复（PR）计划对成年CF患者心理健康、睡眠质量和生活质量的影响。
共有22名成年CF患者被随机分配到干预组（PR + PMR）或对照组（仅PR）。在基线、干预21天后和48天随访时进行评估。结果指标包括用于生活质量评估的CFQ-R、用于心理健康评估的HADS和用于睡眠评估的PSQI。
与对照组相比，进行PMR的参与者在最终评估时焦虑（P = 0.05）和抑郁（P = 0.02）显著降低。睡眠质量也有显著改善（P < 0.01）。在肺功能或六分钟步行试验表现方面未发现相关差异。
将PMR纳入肺康复计划可能是改善CF患者心理健康和睡眠的有效策略。由于其可及性和易于实施，PMR可作为这些患者整体护理的补充方法采用。
