Doorley James, Greenberg Jonathan, Stauder Matthew, Vranceanu Ana-Maria
Integrated Brain Health Clinical and Research Program, Massachusetts General Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
Mindfulness (N Y). 2021 Nov;12(11):2672-2680. doi: 10.1007/s12671-021-01729-y. Epub 2021 Sep 1.
Poor sleep quality is prevalent among individuals with chronic pain and contributes to increased physical and emotional dysfunction. However, treatments that improve sleep quality among individuals with chronic pain are scant. A previously developed mind-body activity program for chronic pain has been shown to be feasible and associated with improvements in pain and physical and emotional function. Using secondary data-analysis, the purpose of this study was to understand whether participants also experienced significant and sustained improvements in sleep quality over time and whether these improvements were explained by change in two core treatment targets, relaxation and mindfulness.
Participants with heterogenous chronic pain ( = 82) were randomized to a mind-body activity intervention with (=41) or without (; =41) a Fitbit device. Sleep quality was measured with the PSQI, mindfulness with the CAMS-R, and relaxation with the relaxation subscale of the MOCS-A. Mediation was tested via mixed-models analysis.
Both intervention groups experienced significant and comparable improvements in sleep quality from baseline to post-treatment, which were sustained through a 3-month follow-up. Mindfulness and relaxation also improved significantly over time and these improvements were associated with improved sleep quality. Mindfulness and relaxation fully mediated improvement in sleep quality (medium to large effect sizes).
Results suggest that, despite not targeting sleep explicitly, the two mind-body activity programs hold promise for sustainably improving sleep quality among patients with chronic pain. Targeting mindfulness and relaxation may facilitate these improvements.
睡眠质量差在慢性疼痛患者中普遍存在,且会导致身体和情绪功能障碍加剧。然而,改善慢性疼痛患者睡眠质量的治疗方法却很少。先前开发的一项针对慢性疼痛的身心活动计划已被证明是可行的,且与疼痛、身体和情绪功能的改善相关。本研究通过二次数据分析,旨在了解参与者的睡眠质量是否也会随着时间的推移而得到显著且持续的改善,以及这些改善是否可以通过两个核心治疗目标(放松和正念)的变化来解释。
患有多种慢性疼痛的参与者(n = 82)被随机分为接受身心活动干预(n = 41)组,该组配备(n = 41)或不配备(n = 41)Fitbit设备。使用匹兹堡睡眠质量指数(PSQI)测量睡眠质量,使用正念注意觉知量表修订版(CAMS-R)测量正念,使用多维疼痛应对策略问卷-放松分量表(MOCS-A)测量放松。通过混合模型分析来检验中介作用。
两个干预组从基线到治疗后的睡眠质量均有显著且相当的改善,且在3个月的随访中持续存在。随着时间的推移,正念和放松也有显著改善,这些改善与睡眠质量的提高相关。正念和放松完全介导了睡眠质量的改善(效应量为中等至大)。
结果表明,尽管没有明确针对睡眠,但这两个身心活动计划有望持续改善慢性疼痛患者的睡眠质量。针对正念和放松可能有助于这些改善。