April-Sanders Ayana K, Tehranifar Parisa, Terry Mary Beth, Crookes Danielle M, Isasi Carmen R, Gallo Linda C, Fernandez-Rhodes Lindsay, Perreira Krista M, Daviglus Martha L, Suglia Shakira F
Department of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, NJ 08854, USA.
Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA.
Int J Environ Res Public Health. 2025 Apr 7;22(4):576. doi: 10.3390/ijerph22040576.
Previous studies have examined the association between family dysfunction and pubertal timing in adolescent girls. However, the evidence is lacking on the role of family dysfunction during sensitive developmental periods in both boys and girls from racial and ethnic minority groups. This study aimed to determine the effect of family dysfunction on the timing of pubertal maturation among US Hispanic/Latino children and adolescents. Participants were 1466 youths (50% female; ages 8-16 years) from the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth). Pubertal maturation was measured using self-administered Pubertal Development Scale (PDS) items for boys and girls. Family dysfunction included measures of single-parent family structure, unhealthy family functioning, low parental closeness, and neglectful parenting style. We used multivariable ordinal logistic and linear regression analyses to examine the associations between family dysfunction and pubertal maturation (individual and cumulative measures), with adjustment for childhood BMI and socioeconomic factors, design effects (strata and clustering), and sample weights. Multivariable models of individual PDS items showed that family dysfunction was negatively associated with growth in height (OR = 0.66, 95% CI: 0.44, 0.99) in girls; no associations were found in boys. In the assessment of cumulative PDS scores, family dysfunction was associated with a lower average pubertal maturation score (b = -0.63, 95% CI: -1.21, -0.05) in boys, while no associations were found in girls. Pubertal timing lies at the intersection of associations between childhood adversity and adult health and warrants further investigation to understand the factors affecting timing and differences across sex and sociocultural background.
以往的研究探讨了家庭功能障碍与少女青春期发育时间之间的关联。然而,关于家庭功能障碍在种族和少数民族群体中男孩和女孩敏感发育阶段所起的作用,目前证据不足。本研究旨在确定家庭功能障碍对美国西班牙裔/拉丁裔儿童及青少年青春期成熟时间的影响。研究对象为1466名来自西班牙裔社区儿童健康研究/拉丁裔青年研究(SOL青年研究)的青少年(50%为女性;年龄在8至16岁之间)。青春期成熟情况通过男孩和女孩自行填写的青春期发育量表(PDS)项目进行测量。家庭功能障碍包括单亲家庭结构、不健康的家庭功能、父母亲密程度低以及忽视型养育方式等指标。我们使用多变量有序逻辑回归和线性回归分析,来检验家庭功能障碍与青春期成熟(个体及累积测量指标)之间的关联,并对儿童BMI和社会经济因素、设计效应(分层和聚类)以及样本权重进行了调整。个体PDS项目的多变量模型显示,家庭功能障碍与女孩身高增长呈负相关(OR = 0.66,95% CI:0.44,0.99);在男孩中未发现相关性。在累积PDS评分评估中,家庭功能障碍与男孩较低的平均青春期成熟评分相关(b = -0.63,95% CI:-1.21,-0.05),而在女孩中未发现相关性。青春期发育时间处于儿童期逆境与成人健康之间关联的交叉点,有必要进一步开展研究,以了解影响发育时间的因素以及性别和社会文化背景方面的差异。