Bonfiglio Caterina, Tatoli Rossella, Donghia Rossella, Pesole Pasqua Letizia, Giannelli Gianluigi
Unit of Data Science, National Institute of Gastroenterology-IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
Core Facility Biobank, National Institute of Gastroenterology IRCCS "Saverio de Bellis", Castellana Grotte, 70013 Bari, Italy.
Nutrients. 2025 Apr 17;17(8):1370. doi: 10.3390/nu17081370.
: Poultry meat is currently among the most widely consumed meats in Italy and worldwide. Poultry is reasonably affordable and accessible, explaining the high global consumption rates. This population-based prospective cohort study investigated the association between meat consumption and gastrointestinal cancers (GCs) and other causes of mortality in southern Italy. : Data were collected from 4869 participants in the MICOL and NUTRIHEP cohorts. The EPIC questionnaire was used to elicit information on food and drink consumption. For analytical purposes, weekly meat consumption was grouped into four categories: total meat: <200 g, 201-300 g, 301-400 g, and >400 g red meat: <150 g, 150-250 g, 251-350 g, and >350 g; poultry: <100 g, 100-200 g, 201-300 g, and >300 g. Cox proportional hazard regression and competing risk models were employed for statistical analysis. : Analyzing weekly poultry consumption, it was observed that subjects consuming more than 300 g had a 27% higher risk of death from all causes [HR 1.27; 95% CI (1.00; 1.61)] than those consuming less than 100 g. In addition, for GCs, the SHR for weekly poultry consumption above 300 g was 2.27 [95% CI (1.23; 4.17)], a risk that for men increased to 2.61 [95% CI (1.31; 5.19)]. : Our study showed that poultry consumption above 300 g/week is associated with a statistically significant increased mortality risk both from all causes and from GCs. The risk is higher for men than for women.
家禽肉目前是意大利乃至全球消费最为广泛的肉类之一。家禽价格合理且易于获取，这解释了其在全球的高消费率。这项基于人群的前瞻性队列研究调查了意大利南部肉类消费与胃肠道癌症（GCs）以及其他死亡原因之间的关联。
数据收集自MICOL和NUTRIHEP队列中的4869名参与者。使用EPIC问卷来获取有关食物和饮料消费的信息。为了进行分析，每周肉类消费被分为四类：总肉类：<200克、201 - 300克、301 - 400克和>400克；红肉：<150克、150 - 250克、251 - 350克和>350克；家禽：<100克、100 - 200克、201 - 300克和>300克。采用Cox比例风险回归和竞争风险模型进行统计分析。
分析每周家禽消费情况时发现，消费超过300克的受试者比消费少于100克的受试者全因死亡风险高27%[风险比（HR）1.27；95%置信区间（CI）（1.00；1.61）]。此外，对于胃肠道癌症，每周家禽消费超过300克的标准化死亡风险比（SHR）为2.27[95% CI（1.23；4.17）]，男性的这一风险增加至2.61[95% CI（1.31；5.19）]。
我们的研究表明，每周消费超过300克家禽与全因死亡率和胃肠道癌症死亡率在统计学上显著增加相关。男性的风险高于女性。
