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“时间存量”法:经济评估中计算间接成本和效益的新方法。

The "Stock of Time" Method: A New Approach to Calculate Indirect Costs and Benefits in Economic Evaluations.

作者信息

Kok Lucy, Koopmans Carl

机构信息

SEO Amsterdam Economics, University of Amsterdam, The Netherlands.

Vrije Universiteit Amsterdam, The Netherlands.

出版信息

Med Decis Making. 2025 Jul;45(5):614-622. doi: 10.1177/0272989X251333787. Epub 2025 Apr 25.

DOI:10.1177/0272989X251333787
PMID:40285335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12166135/
Abstract

BackgroundHealth interventions affect people's welfare directly by impacting people's health but also indirectly via a change in consumption and leisure time caused by the change in health. This study discusses 2 ongoing issues in the economic evaluation of health interventions. The first is how to value a change in the amount of leisure time of a patient. The second issue concerns the valuation of a change in production.MethodsWe present a theoretical model that assumes that individual utility depends on health, consumption, and leisure time. We assume that the total stock of time consists of 3 components: leisure time, working time, and recovery time. The model takes a societal perspective and assumes that individuals optimize their utility, conditional on time and budget restrictions.ResultsFor the first issue, the model indicates that the value of a change in the stock of time available for leisure and work has to be added to the direct effects of a health intervention, instead of only a change in work hours. For the second issue, the model indicates that in case of a change in longevity, only the change in taxes paid may be counted because the income change is included in the value of the change in quality-adjusted life-years. A numerical example shows that this approach may counterbalance the potential overestimation of the welfare effects of treatments with the human capital method and underestimation related to the friction cost method.ConclusionWe propose a new method that includes the welfare effects of health interventions due to a change in the amount of leisure time and avoids double counting of welfare changes, which are included in the direct effects.HighlightsWe present a theoretical model and use it to analyze 2 issues in the economic evaluation of health interventions: the inclusion of leisure time and the valuation of production.The model indicates that the effects of health changes on the amount of both work and leisure hours need to be taken into account in economic evaluation.As to the valuation of production, the model indicates that in case of a change in longevity, only the change in taxes may be counted.We propose the "stock of time" method to value changes in working hours and leisure hours, which may counterbalance potential overestimates and underestimates in established methods.

摘要

背景

健康干预措施不仅通过影响人们的健康直接影响其福利,还会因健康变化导致消费和休闲时间的改变而间接产生影响。本研究探讨了健康干预措施经济评估中的两个现存问题。第一个问题是如何评估患者休闲时间量的变化。第二个问题涉及生产变化的评估。

方法

我们提出了一个理论模型,该模型假定个人效用取决于健康、消费和休闲时间。我们假设时间的总存量由三个部分组成:休闲时间、工作时间和恢复时间。该模型从社会角度出发,假定个人在时间和预算限制条件下实现效用最大化。

结果

对于第一个问题,该模型表明,必须将可用于休闲和工作的时间存量变化的价值加到健康干预的直接影响上,而不仅仅是工作时间的变化。对于第二个问题,该模型表明,在寿命发生变化的情况下,仅可计算所缴纳税款的变化,因为收入变化已包含在质量调整生命年变化的价值中。一个数值示例表明,这种方法可能会抵消人力资本法对治疗福利效应的潜在高估以及摩擦成本法相关的低估。

结论

我们提出了一种新方法,该方法纳入了因休闲时间量变化而产生的健康干预的福利效应,并避免了对已包含在直接效应中的福利变化进行重复计算。

要点

我们提出了一个理论模型,并利用它来分析健康干预措施经济评估中的两个问题:休闲时间的纳入和生产的评估。

该模型表明,在经济评估中需要考虑健康变化对工作和休闲时间量的影响。

关于生产的评估,该模型表明,在寿命发生变化的情况下,仅可计算税款的变化。

我们提出了“时间存量”方法来评估工作时间和休闲时间的变化,这可能会抵消既定方法中的潜在高估和低估。

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本文引用的文献

1
Incorporating productivity loss in health economic evaluations: a review of guidelines and practices worldwide for research agenda in China.将生产力损失纳入健康经济评估:对全球指南和实践的综述,以及对中国研究议程的启示。
BMJ Glob Health. 2022 Aug;7(8). doi: 10.1136/bmjgh-2022-009777.
2
Time Is Money: Investigating the Value of Leisure Time and Unpaid Work.时间就是金钱:探究闲暇时间和无偿工作的价值。
Value Health. 2018 Dec;21(12):1428-1436. doi: 10.1016/j.jval.2018.04.1828. Epub 2018 Jul 14.
3
Estimated annual and lifetime labor productivity in the United States, 2016: implications for economic evaluations.2016 年美国年度和终生劳动力生产力估计:对经济评估的影响。
J Med Econ. 2019 Jun;22(6):501-508. doi: 10.1080/13696998.2018.1542520. Epub 2018 Nov 15.
4
Recommendations for Conduct, Methodological Practices, and Reporting of Cost-effectiveness Analyses: Second Panel on Cost-Effectiveness in Health and Medicine.《健康与医疗领域成本效益分析的实施、方法学实践和报告推荐:第二版》。
JAMA. 2016 Sep 13;316(10):1093-103. doi: 10.1001/jama.2016.12195.
5
Health, Health-Related Quality of Life, and Quality of Life: What is the Difference?健康、健康相关生活质量和生活质量:有何区别?
Pharmacoeconomics. 2016 Jul;34(7):645-9. doi: 10.1007/s40273-016-0389-9.
6
Productivity Losses Associated with Head and Neck Cancer Using the Human Capital and Friction Cost Approaches.使用人力资本法和摩擦成本法评估头颈癌导致的生产力损失
Appl Health Econ Health Policy. 2015 Aug;13(4):359-67. doi: 10.1007/s40258-015-0155-8.
7
Estimating productivity costs using the friction cost approach in practice: a systematic review.使用摩擦成本法估算实际生产中的成本:系统综述。
Eur J Health Econ. 2016 Jan;17(1):31-44. doi: 10.1007/s10198-014-0652-y. Epub 2014 Nov 12.
8
Health status and the allocation of time.健康状况与时间分配。
Health Econ. 2012 May;21(5):514-27. doi: 10.1002/hec.1725. Epub 2011 Mar 8.
9
The incorporation of income and leisure in health state valuations when the measure is silent: an empirical inquiry into the sound of silence.将收入和闲暇纳入健康状况评估中,当衡量标准保持沉默时:对沉默之声的实证探究。
Med Decis Making. 2009 Jul-Aug;29(4):503-12. doi: 10.1177/0272989X09336161. Epub 2009 Jun 9.
10
Breaking the silence: exploring the potential effects of explicit instructions on incorporating income and leisure in TTO exercises.打破沉默:探讨明确指示对在时间权衡法练习中纳入收入和休闲的潜在影响。
Value Health. 2009 Jan-Feb;12(1):172-80. doi: 10.1111/j.1524-4733.2008.00406.x. Epub 2008 Jul 18.