Kaboodkhani Reza, Soltani Sajjad, Yousufzai Shayan, Fatehi Negar, Nadgaran Mahsan, Yousefi Alireza
Otolaryngology, Head and neck Surgery Department, Otolaryngology Research Center, Khalili Hospital, Shiraz University Medical Sciences, P.O. Box: 71348-14336, Shiraz, Iran.
Otolaryngology, Head and neck Surgery Department, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Surg Case Rep. 2025 Jun;131:111333. doi: 10.1016/j.ijscr.2025.111333. Epub 2025 Apr 21.
BCC (BCC) is the most common form of nonmelanocytic skin cancer, particularly prevalent in sun-exposed areas like the head and neck. BCC in the nasal vestibule is rare, with an incidence of only 0.01 %. This case report examines the clinical presentation and management of BCC in this unusual location.
A 65-year-old male with no significant medical history presented with a two-year history of a mass sensation in the left nasal vestibule, accompanied by recurrent epistaxis. Examination revealed a firm, rubbery, and ulcerated 1 cm mass. Histopathologic findings confirmed Micronodular BCC, leading to surgical excision and reconstruction using posterior auricular skin. Despite successful removal, pathological analysis showed positive margins, necessitating careful follow-up.
The report discusses the rising global incidence of BCC due to increased solar exposure and an aging population, with 80 % of cases occurring in the head and neck. While the nasal tip and upper lateral surface are common sites, BCC in the nasal vestibule is exceedingly rare. Differential diagnoses include various premalignant and malignant conditions. Surgical excision with adequate margins is the preferred treatment, alongside options like topical agents and Mohs micrographic surgery for less advanced cases. The challenges of tissue reconstruction post-excision are addressed, recommending total skin grafts or specific flaps depending on tissue loss.
This report highlights the rarity and clinical significance of BCC in the nasal vestibule, advocating for increased awareness among healthcare professionals regarding atypical skin cancer presentations and emphasizing the importance of early detection and management.
基底细胞癌(BCC)是最常见的非黑素细胞性皮肤癌,在头颈部等阳光暴露部位尤为普遍。鼻前庭的基底细胞癌较为罕见,发病率仅为0.01%。本病例报告探讨了这种罕见部位基底细胞癌的临床表现及治疗方法。
一名65岁男性,无重大病史,左侧鼻前庭有肿物感两年,伴有反复鼻出血。检查发现一个质地硬、似橡皮样且溃疡的1厘米肿物。组织病理学检查确诊为微结节型基底细胞癌,遂行手术切除并用耳后皮肤进行重建。尽管成功切除,但病理分析显示切缘阳性,需要密切随访。
报告讨论了由于阳光照射增加和人口老龄化,全球基底细胞癌发病率不断上升,80%的病例发生在头颈部。鼻尖和鼻上外侧是常见部位,而鼻前庭的基底细胞癌极为罕见。鉴别诊断包括各种癌前病变和恶性病变。手术切除时保证足够切缘是首选治疗方法,对于病情较轻的病例,还可选择外用药物和莫氏显微外科手术等。文中还探讨了切除后组织重建的挑战,建议根据组织缺损情况选择全厚皮片移植或特定皮瓣。
本报告强调了鼻前庭基底细胞癌的罕见性及临床意义,提倡医护人员提高对非典型皮肤癌表现的认识,并强调早期发现和治疗的重要性。