多巴胺和去甲肾上腺素受体阻断在抗精神病药物作用中的相对作用：以甲氧氯普胺、硫乙拉嗪和吗茚酮作为药理学工具 - Suppr

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超能文献

The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: metoclopramide, thiethylperazine, and molindone as pharmacological tools.

作者信息

Robinson S E, Berney S, Mishra R, Sulser F

出版信息

Psychopharmacology (Berl). 1979 Aug 8;64(2):141-7. doi: 10.1007/BF00496054.

DOI:10.1007/BF00496054

PMID:40288

Abstract

摘要

相似文献

The relative role of dopamine and norepinephrine receptor blockade in the action of antipsychotic drugs: metoclopramide, thiethylperazine, and molindone as pharmacological tools.多巴胺和去甲肾上腺素受体阻断在抗精神病药物作用中的相对作用：以甲氧氯普胺、硫乙拉嗪和吗茚酮作为药理学工具

Psychopharmacology (Berl). 1979 Aug 8;64(2):141-7. doi: 10.1007/BF00496054.

Preferential effect of noncataleptogenic neuroleptics on mesolimbic dopaminergic function.非致僵性抗精神病药物对中脑边缘多巴胺能功能的优先作用。

Adv Biochem Psychopharmacol. 1977;16:607-11.

Differential effects of typical and atypical neuroleptics on alpha-noradrenergic and dopaminergic post synaptic receptors.典型和非典型抗精神病药物对α-去甲肾上腺素能和多巴胺能突触后受体的不同作用。

Neuropharmacology. 1979 Jul;18(7):591-4. doi: 10.1016/0028-3908(79)90109-6.

[Current theories on the role of dopamine in the mechanism of action of neuroleptic drugs].[关于多巴胺在抗精神病药物作用机制中的作用的当前理论]

Psychiatr Pol. 1984 Jan-Feb;18(1):39-47.

Effects on striatal and mesolimbic dopamine systems of a new potential antipsychotic drug -mezilamine- with weak cataleptogenic properties.一种具有弱致僵特性的新型潜在抗精神病药物——美齐拉敏对纹状体和中脑边缘多巴胺系统的影响。

Life Sci. 1978 Jul 17;23(3):261-73. doi: 10.1016/0024-3205(78)90314-4.

A comparison of the effects of anti-psychotic drugs on pituitary, striatal and limbic system post-synaptic dopamine receptors.抗精神病药物对垂体、纹状体和边缘系统突触后多巴胺受体影响的比较。

Life Sci. 1978 Aug 14;23(6):605-9. doi: 10.1016/0024-3205(78)90040-1.

Dopamine D-2 receptors inhibit D-1 stimulated cyclic AMP accumulation in striatum but not limbic forebrain.多巴胺D-2受体抑制纹状体中由D-1受体刺激引起的环磷酸腺苷积累，但对边缘前脑无此作用。

Naunyn Schmiedebergs Arch Pharmacol. 1987 May;335(5):508-12. doi: 10.1007/BF00169116.

Neuroleptic drugs and the dopamine hypothesis.抗精神病药物与多巴胺假说。

Lancet. 1979 Apr 28;1(8122):934. doi: 10.1016/s0140-6736(79)91424-7.

Drug effects on pre- and postsynaptic dopamine receptors.药物对突触前和突触后多巴胺受体的影响。

Adv Biochem Psychopharmacol. 1980;24:57-64.

The prolactin secretory response to neuroleptic drugs: mechanisms, applications and limitations.催乳素对抗精神病药物的分泌反应：机制、应用及局限性。

Psychoneuroendocrinology. 1980;5(2):121-37. doi: 10.1016/0306-4530(80)90015-3.

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Electrochemical determination of thiethylperazine using semi-graphitized carbon nanofibers-MnO nanocomposite.使用半石墨化碳纳米纤维-MnO纳米复合材料对硫乙拉嗪进行电化学测定。

Mikrochim Acta. 2023 Oct 24;190(11):449. doi: 10.1007/s00604-023-06025-1.

Mimicking of Phase I Metabolism Reactions of Molindone by HLM and Photocatalytic Methods with the Use of UHPLC-MS/MS.利用 UHPLC-MS/MS 通过 HLM 和光催化方法模拟莫林酮的 I 相代谢反应。

Molecules. 2020 Mar 17;25(6):1367. doi: 10.3390/molecules25061367.

Effects of clozapine in a selective muscarinic bioassay and on single cells of the rat hippocampus.氯氮平在选择性毒蕈碱生物测定中以及对大鼠海马单细胞的作用。

Naunyn Schmiedebergs Arch Pharmacol. 1982 Jul;320(1):20-5. doi: 10.1007/BF00499066.

Interactions of a neuroleptic drug (fluphenazine) with catecholamines in hippocampus.一种抗精神病药物（氟奋乃静）与海马体中儿茶酚胺的相互作用。

Psychopharmacology (Berl). 1982;76(2):122-9. doi: 10.1007/BF00435265.

Amphetamine stereotypies and polyribosomal disaggregation in rats: effects of adrenergic and serotonergic blocking agents.大鼠中的苯丙胺刻板行为和多核糖体解聚：肾上腺素能和血清素能阻断剂的作用。

Psychopharmacology (Berl). 1980;72(1):109-10. doi: 10.1007/BF00433815.

Relationship between plasma concentration and arousal in normal subjects after single oral and parenteral doses of melperone, a butyrophenone neuroleptic.单次口服和肠胃外给予丁酰苯类抗精神病药美哌隆后，正常受试者血浆浓度与觉醒之间的关系。

Psychopharmacology (Berl). 1983;79(2-3):111-4. doi: 10.1007/BF00427795.

Typical and atypical neuroleptics are potent antagonists at alpha 1-adrenoceptors of the dorsal lateral geniculate nucleus. An electrophysiological study.典型和非典型抗精神病药物是外侧膝状体核α1 -肾上腺素能受体的强效拮抗剂。一项电生理学研究。

Naunyn Schmiedebergs Arch Pharmacol. 1982 Oct;321(1):32-7. doi: 10.1007/BF00586345.

Electrophysiologic interactions of antipsychotic drugs with central noradrenergic pathways.抗精神病药物与中枢去甲肾上腺素能通路的电生理相互作用。

Psychopharmacology (Berl). 1981;73(2):126-33. doi: 10.1007/BF00429202.

Assessment of anti-psychotic drugs.抗精神病药物的评估。

Br J Clin Pharmacol. 1981 Mar;11(3):225-36. doi: 10.1111/j.1365-2125.1981.tb00526.x.

Metoclopramide: antipsychotic efficacy of a drug lacking potency in receptor models.甲氧氯普胺：一种在受体模型中缺乏效力的药物的抗精神病疗效。

Psychopharmacology (Berl). 1980;71(3):219-25. doi: 10.1007/BF00433055.

本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.氯丙嗪或氟哌啶醇对小鼠脑内3-甲氧基酪胺和去甲变肾上腺素形成的影响。

Acta Pharmacol Toxicol (Copenh). 1963;20:140-4. doi: 10.1111/j.1600-0773.1963.tb01730.x.

On the occurrence of homovanillic acid in brain and cerebrospinal fluid and its determination by a fluorometric method.关于高香草酸在脑和脑脊液中的存在及其荧光法测定

Life Sci (1962). 1963 Jul(7):448-58. doi: 10.1016/0024-3205(63)90132-2.

A fluorimetric method for the estimation of 4-hydroxy-3-methoxyphenylacetic acid (homovanillic acid) and its identification in brain tissue.一种用于估算4-羟基-3-甲氧基苯乙酸（高香草酸）及其在脑组织中鉴定的荧光法。

Br J Pharmacol Chemother. 1963 Feb;20(1):204-13. doi: 10.1111/j.1476-5381.1963.tb01310.x.

The treatment of anergic schizophrenia with imipramine.用丙咪嗪治疗无反应性精神分裂症。

J Clin Exp Psychopathol Q Rev Psychiatry Neurol. 1959 Jul-Sep;20:235-42.

[The antipsychotic effect of thiethylperazine and the clinical experience with its application in psychiatry].[硫乙拉嗪的抗精神病作用及其在精神病学中的临床应用经验]

Cesk Psychiatr. 1967 Feb;63(1):1-8.

[Clinical and electroencephalographic effects of methoclopramide in psychiatry].甲氧氯普胺在精神病学中的临床及脑电图效应

Therapie. 1965 Jul-Aug;20(4):975-95.

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.能否从动物实验数据预测抗精神病药物（强效镇静剂）的临床效果？IV. 一种改进的实验设计，用于测量抗精神病药物对大鼠中苯丙胺或阿扑吗啡诱导的“刻板行为”和“激动”的抑制作用。

Arzneimittelforschung. 1967 Jul;17(7):841-54.

Dystonic reactions in children caused by metoclopramide.胃复安引起的儿童张力障碍反应。

Arch Dis Child. 1970 Feb;45(239):130-3. doi: 10.1136/adc.45.239.130.

[Acute dyskinesia following short-term antiemetic medication].[短期使用止吐药物后出现的急性运动障碍]

Schweiz Med Wochenschr. 1969 Jul 26;99(31):1107-9.

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