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持续护理项目:一项关于住院物质使用治疗后持续护理电话干预的多组随机对照试验。

The continuing care project: A multi-arm randomised controlled trial of a continuing care telephone intervention following residential substance use treatment.

作者信息

Kelly Peter J, Deane Frank P, Baker Amanda L, Townsend Camilla, McKay James R, Degan Tayla J, Nolan Erin, Palazzi Kerrin, Byrne Gerard, Osborne Briony, Meyer Johanna, Robinson Laura, Oldmeadow Christopher, Lawson Kenny, Searles Andrew, Lunn Joanne, Nunes Jason, Ingram Isabella

机构信息

School of Psychology, University of Wollongong, New South Wales, Australia.

National Drug and Alcohol Research Centre, University of New South Wales, Australia.

出版信息

Drug Alcohol Depend. 2025 Jul 1;272:112668. doi: 10.1016/j.drugalcdep.2025.112668. Epub 2025 Apr 5.

Abstract

BACKGROUND

Previous research suggests telephone-delivered continuing care interventions are effective in reducing rates of substance use. This study assessed the effectiveness of telephone-delivered continuing care for people who had stayed in a residential alcohol and other drug (AOD) treatment facility for at least 4-weeks.

METHODS

Participants were 277 (20 - 71 years; M = 38 years, SD = 10.4; 58 % male) individuals attending residential AOD treatment. Following discharge participants were randomised to: i) 12 weekly telephone sessions; ii) 4 weekly telephone sessions; or iii) no telephone sessions (control group). A multi-centre prospective, randomised, open, blinded endpoint (PROBE) design compared three study arms with follow up at 3- and 6-months. Primary outcome was the odds of complete abstinence and the days of AOD use for those not completely abstinent at 6-months.

RESULTS

At 6-months follow-up, the odds of being completely abstinent in the past month was not significantly different between the three study arms (p > 0.6) and the number of days abstinent was not significantly different (p > 0.4). Participants across all arms were more likely (p <  0.001) to be completely abstinent compared to baseline [12-session OR = 12.86 (5.4, 30.9); 4-session OR = 9.52 (4.0, 22.4); Control OR = 7.02, (3.4, 14.7)].

CONCLUSIONS

The results suggest that the residential programs are associated with positive long-term impacts among participants who complete at least 4 weeks of treatment. Further continuing care research should include those who do not remain in treatment for at least 4 weeks, as they may be likely to benefit the most.

摘要

背景

先前的研究表明,通过电话提供的持续护理干预措施在降低药物使用发生率方面是有效的。本研究评估了为在住院酒精和其他药物(AOD)治疗机构停留至少4周的人群通过电话提供持续护理的效果。

方法

参与者为277名(年龄20 - 71岁;平均年龄M = 38岁,标准差SD = 10.4;58%为男性)接受住院AOD治疗的个体。出院后,参与者被随机分为:i)12次每周一次的电话咨询;ii)4次每周一次的电话咨询;或iii)无电话咨询(对照组)。采用多中心前瞻性、随机、开放、盲终点(PROBE)设计,对三个研究组进行比较,并在3个月和6个月时进行随访。主要结局是完全戒酒的几率以及6个月时未完全戒酒者的AOD使用天数。

结果

在6个月的随访中,三个研究组在过去一个月完全戒酒的几率没有显著差异(p > 0.6),戒酒天数也没有显著差异(p > 0.4)。与基线相比,所有组的参与者更有可能完全戒酒(p < 0.001)[12次咨询组的优势比OR = 12.86(5.4,30.9);4次咨询组的优势比OR = 9.52(4.0,22.4);对照组的优势比OR = 7.02,(3.4,14.7)]。

结论

结果表明,住院治疗项目对完成至少4周治疗的参与者具有积极的长期影响。进一步的持续护理研究应纳入那些未接受至少4周治疗的人群,因为他们可能受益最大。

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