Kijpaisalratana Norawit, El Ariss Abdel Badih, Balk Adi, Mitragotri Suhanee, Samadian Kian D, Hahn Barry J, Coleska Adriana, Baugh Joshua J, Hassan Ahmad, Lee Jarone, Raja Ali S, He Shuhan
Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States of America; Department of Emergency Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, United States of America.
Am J Emerg Med. 2025 Aug;94:125-132. doi: 10.1016/j.ajem.2025.04.045. Epub 2025 Apr 23.
Hospital readmissions often result from a combination of factors, including inadequate follow-up care, poor discharge planning, patient non-adherence, and social determinants of health (SDOH) that impact access to healthcare and follow-up resources, many of which are beyond provider control. Enhanced post-discharge strategies, including risk stratification, are essential. This study aims to develop and validate the Discharge Severity Index (DSI) to predict readmission risk and optimize resource allocation for effective follow-up care.
This single-center retrospective study analyzed ED visits from the Medical Information Mart for Intensive Care IV, dividing the data into derivation (75 %) and validation (25 %) cohorts. Univariate analyses were conducted on factors commonly available for most discharges, including patient age, the latest vital signs recorded, medical complexity, and ED length of stay (LOS). Multiple logistic regression (MLR) was employed to identify independent risk factors of patients revisiting the ED within a week and being subsequently admitted to the hospital. Adjusted parameter estimates from the MLR were used to develop a predictive model.
Among 229,920 patients discharged from the ED, 1.92 % were readmitted. The analysis identified seven variables correlated with this outcome, with six significant risk factors pinpointed through MLR: age above 65, heart rate over 100, and oxygen saturation below 96 % (assigned 1 point each), along with having more than five active medications administered during the hospital stay or a LOS exceeding 3 h (assigned 2 points each). Using these scores, we categorized patients into five DSI groups, reflecting escalating readmission risk from DSI 5 (lowest risk) to DSI 1 (highest risk): DSI 5 (0; OR: 1.0), DSI 4 (1-2; OR: 3.49), DSI 3 (3-4; OR: 8.44), DSI 2 (5-6; OR: 11.65), and DSI 1 (>6; OR: 14.63). The seven-day readmission rates were comparable between the development and validation cohorts. For instance, for DSI 1, the rates were 5.16 % in the development cohort and 4.67 % in the validation cohort. For DSI 2, the rates were 4.16 % and 4.04 %, respectively.
This study seeks to develop and validate the DSI, proposing its effectiveness as a tool for healthcare providers to categorize patients by their risk of post-discharge admission from the ED. The utilization of this tool has the potential to lead to a more informed allocation of resources after discharge.
医院再入院通常是多种因素共同作用的结果,包括后续护理不足、出院计划不完善、患者依从性差以及影响获得医疗保健和后续资源的健康社会决定因素(SDOH),其中许多因素超出了医疗服务提供者的控制范围。强化出院后策略,包括风险分层,至关重要。本研究旨在开发并验证出院严重程度指数(DSI),以预测再入院风险并优化资源分配,实现有效的后续护理。
这项单中心回顾性研究分析了重症监护IV医疗信息集市中的急诊就诊情况,将数据分为推导队列(75%)和验证队列(25%)。对大多数出院病例通常可用的因素进行单因素分析,包括患者年龄、记录的最新生命体征、医疗复杂性和急诊住院时间(LOS)。采用多元逻辑回归(MLR)来确定患者在一周内再次就诊并随后入院的独立危险因素。MLR的调整参数估计值用于建立预测模型。
在从急诊室出院的229,920名患者中,1.92%再次入院。分析确定了与该结果相关的七个变量,通过MLR确定了六个显著危险因素:65岁以上、心率超过100次/分、血氧饱和度低于96%(各计1分),以及住院期间使用超过五种活性药物或住院时间超过3小时(各计2分)。利用这些分数,我们将患者分为五个DSI组,反映从DSI 5(最低风险)到DSI 1(最高风险)不断上升的再入院风险:DSI 5(0;OR:1.0)、DSI 4(1 - 2;OR:3.49)、DSI 3(3 - 4;OR:8.44)、DSI 2(5 - 6;OR:11.65)和DSI 1(>6;OR:14.63)。推导队列和验证队列的七天再入院率相当。例如,对于DSI 1,推导队列中的比率为5.16%,验证队列中的比率为4.67%。对于DSI 2,比率分别为4.16%和4.04%。
本研究旨在开发并验证DSI,提出其作为医疗服务提供者按患者从急诊室出院后再入院风险进行分类的工具的有效性。使用该工具有可能在出院后实现更明智的资源分配。