Trento Guilherme, Davila Christian, Nafz Johann Ludwig, Jaber Mona, Jung Susanne, Lisson Jacqueline, Schulte Miriam, Kleinheinz Johannes
Department of Cranio-Maxillofacial Surgery, University Hospital Münster, Münster, Germany.
Department of Cranio-Maxillofacial Surgery, University Hospital Münster, Münster, Germany.
J Stomatol Oral Maxillofac Surg. 2025 Oct;126(5S):102381. doi: 10.1016/j.jormas.2025.102381. Epub 2025 Apr 25.
Congenital head and neck malformations frequently pose a significant diagnostic challenge for physicians. Less than 10% of congenital teratomas occur in the head and neck region. The identification of these lesions is often a serendipitous finding on prenatal ultrasound. Surgical intervention may be required immediately post-birth depending on the location and dimensions of the identified teratoma. The objectives of the current study are to present three cases of mature teratoma, diagnosed post-birth, in newborn male patients and to bring attention to the difficulties in the treatment of such a condition. All cases were diagnosed as G0, according to the Gonzalez-Crussi grading system. Following the protocols of the MAKEI study group, the treatment and follow-up plans were established. Based on the results so far achieved, and the experience acquired from these reported cases, it can be suggested that teratomas, primarily located in the nasopharynx region, have surgical resection as the first line of treatment. Additionally, long-term follow-ups should be performed periodically through different types of exams, such as imaging and laboratory exams.
先天性头颈部畸形常常给医生带来重大的诊断挑战。不到10%的先天性畸胎瘤发生在头颈部区域。这些病变的识别通常是产前超声检查时的偶然发现。根据所识别畸胎瘤的位置和大小,出生后可能需要立即进行手术干预。本研究的目的是介绍3例出生后诊断为成熟畸胎瘤的新生儿男性患者,并引起人们对治疗这种疾病困难的关注。根据冈萨雷斯-克鲁西分级系统,所有病例均诊断为G0级。按照MAKEI研究组的方案,制定了治疗和随访计划。根据目前取得的结果以及从这些报告病例中获得的经验,可以建议主要位于鼻咽部区域的畸胎瘤,手术切除应作为一线治疗方法。此外,应通过不同类型的检查,如影像学和实验室检查,定期进行长期随访。