[Malignant melanomas in pregnancy].

A malignant melanoma was diagnosed and treated during pregnancy in twelve patients average age 29 (19-38) years. Eleven patients were in stage I and one in stage II. One patient presented with 2 primary malignant melanomas. There was no essential difference in localisation or melanoma type in comparison with non-pregnant melanoma patients. From histological criteria (tumor thickness and prognostic index) eight patients in stage I had an intermediate and three a high risk of metastases. When compared with non-pregnant melanoma patients the pregnant patients presented with relatively more melanomas having intermediate and high metastases risk. No prediction as to the course of the disease can be made because of the small number of patients. Published data show, however, that in a pregnant subgroup pregnancy has a negative influence on the course of malignant melanoma.