Allali Malika, Errafii Khaoula, Lamsisi Maryame, Fichtali Karima, El Majjaoui Sanae, El Fazazi Hicham, Al Idrissi Najib, El Ghanmi Adil, Ghanmi Lahcen, Ghazi Bouchra, Ismaili Nabil, Rhalem Wajih, Ghazal Hassan, Bakri Youssef, Hamdi Salsabil
Virology and Public Health Laboratory, Serum and Vaccine Center (Institut Pasteur du Maroc), Casablanca, Morocco.
Laboratory of Human Pathologies Biology, Department of Biology and Genomic Center of Human Pathologies, Faculty of Sciences, University Mohammed V, Rabat, Morocco.
Pan Afr Med J. 2025 Jan 7;50:11. doi: 10.11604/pamj.2025.50.11.43975. eCollection 2025.
Cervical cancer (CC) stands as the second most prevalent cancer among women in Morocco, with an estimated annual incidence of 2165 cases and over 1199 associated deaths. However, the lack of a comprehensive national registry requires caution in interpreting these figures. This review highlights the examination of the epidemiological profile, diagnostic modalities, risk factors, treatment, and prevention related to CC screening within the context of Morocco. High-risk subtypes of the human papillomavirus (HPV) are the etiological cause of the disease in most cases. Underscoring the urgent need for a thorough understanding of its epidemiological landscape. Other risk factors as age of sexual debut, sexual partners and sexually transmitted infections, immunosuppression, smoking, and parity should be studied comprehensively. Treatment modalities for CC are contingent upon disease staging at diagnosis and the availability of local healthcare resources. Options encompass radical hysterectomy and chemoradiation. The Ministry of Health's endorsement of the vaccine in 2022 marked a significant milestone in combating cancer through prevention and treatment, as it integrated the HPV vaccination into the national vaccination program, targeting girls aged 11 years. Morocco's healthcare landscape underwent significant reforms, culminating in the implementation of compulsory basic medical coverage in 2020 to ensure equitable access to healthcare services for all citizens. Consequently, this proactive approach holds promise for enhancing care standards and substantially curtailing mortality rates attributable to cancer across Morocco in the coming years.
宫颈癌(CC)是摩洛哥女性中第二大常见癌症,估计年发病率为2165例,相关死亡人数超过1199人。然而,由于缺乏全面的国家登记处,在解读这些数据时需谨慎。本综述着重探讨了摩洛哥背景下与宫颈癌筛查相关的流行病学概况、诊断方式、风险因素、治疗及预防。在大多数情况下,高危型人乳头瘤病毒(HPV)是该疾病的病因,这凸显了全面了解其流行病学情况的迫切需求。其他风险因素,如首次性行为年龄、性伴侣及性传播感染、免疫抑制、吸烟和生育情况等,也应进行全面研究。宫颈癌的治疗方式取决于诊断时的疾病分期以及当地医疗资源的可及性。治疗选择包括根治性子宫切除术和放化疗。2022年卫生部批准该疫苗,这是通过预防和治疗抗击癌症的一个重要里程碑,因为它将HPV疫苗纳入了国家疫苗接种计划,目标人群为11岁女孩。摩洛哥的医疗格局经历了重大改革,最终在2020年实施了强制性基本医疗保险,以确保所有公民公平获得医疗服务。因此,这种积极主动的做法有望在未来几年提高摩洛哥的医疗标准,并大幅降低癌症导致的死亡率。