Liu Junyu, Chen Ziyi, Tao Sian, Shu Xinyao, Shao Bingjie, Zhang Xiaobo, Yang Yang, Wang Xiaoli
College of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Institute of Traditional Chinese Medicine of Sichuan Academy of Chinese Medicine Sciences, Chengdu, Sichuan, China.
Front Pharmacol. 2025 Apr 1;16:1557136. doi: 10.3389/fphar.2025.1557136. eCollection 2025.
L. is a perennial marsh botanical drugs belonging to the genus of the family Typhaceae, boasts a medicinal legacy spanning over 1900 years in China. Within traditional medicine, it is often used to treat a variety of bleeding disorders and gynecological diseases. contains various active components and metabolites including flavonoids, steroids, phenylpropanoids and organic acids. Over 94 compounds have been isolated and identified from , demonstrating significant pharmacological activities such as anti-inflammatory, analgesic, anti-platelet aggregation, anti-atherosclerosis and anti-oxidation. In modern clinical practice, is extensively utilized in treating dysmenorrhea, irregular menstruation, trauma bleeding, soft tissue contusion, hematochezia, hematuria and abnormal uterine bleeding. has a wide range of biological activities, making it a valuable resource for discovering potential drug candidates and developing new botanical supplements. This paper provides a comprehensive review of the research status of , encompassing its botany, traditional uses, phytochemistry, pharmacological activity, and quality control, with the objective of enhancing our understanding of the application value and bioavailability of this traditional medicinal plant and offering a reference point for further research in this field.
芦根是一种多年生沼泽植物药,属于香蒲科香蒲属,在中国拥有超过1900年的药用历史。在传统医学中,它常被用于治疗各种出血性疾病和妇科疾病。芦根含有多种活性成分和代谢产物,包括黄酮类、甾体类、苯丙素类和有机酸。已从芦根中分离并鉴定出94种以上的化合物,显示出显著的药理活性,如抗炎、镇痛、抗血小板聚集、抗动脉粥样硬化和抗氧化。在现代临床实践中,芦根被广泛用于治疗痛经、月经不调、外伤出血、软组织挫伤、便血、血尿和子宫异常出血。芦根具有广泛的生物活性,使其成为发现潜在药物候选物和开发新型植物补充剂的宝贵资源。本文对芦根的研究现状进行了全面综述,包括其植物学、传统用途、植物化学、药理活性和质量控制,旨在加深我们对这种传统药用植物应用价值和生物利用度的理解,并为该领域的进一步研究提供参考。