Li Zong-Yang, Li Tong, Cai Hong-Qiao
Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
World J Clin Oncol. 2025 Apr 24;16(4):103343. doi: 10.5306/wjco.v16.i4.103343.
This editorial discusses Thompson 's original article, which is published in the most recent edition of the and sheds critical light on the intertwined issues of health anxiety and work loss in individuals diagnosed with serrated polyposis syndrome (SPS). SPS is rare, characterized by the development of multiple serrated colorectal polyps. This editorial provides an overview of SPS, including its pathophysiology, clinical presentation, diagnostic criteria, management strategies, and the psychosocial impact. SPS is linked to molecular alterations, which drive carcinogenesis. Colonoscopy and histological analysis are used for diagnosis. Genetic testing is also considered where there is a family history. Quality of life can be greatly impacted by the psychosocial effects of SPS, especially health anxiety. Further understanding of the molecular mechanisms and creating individualized surveillance are required.
这篇社论讨论了汤普森的原创文章，该文章发表在最新一期的[期刊名称未给出]上，对被诊断为锯齿状息肉综合征（SPS）的个体中健康焦虑和工作丧失这两个相互交织的问题进行了批判性审视。SPS很罕见，其特征是多发性锯齿状结直肠息肉的形成。这篇社论概述了SPS，包括其病理生理学、临床表现、诊断标准、管理策略以及社会心理影响。SPS与驱动致癌作用的分子改变有关。结肠镜检查和组织学分析用于诊断。有家族病史时也会考虑进行基因检测。SPS的社会心理影响，尤其是健康焦虑，会对生活质量产生重大影响。需要进一步了解分子机制并制定个性化监测方案。
