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JAK inhibitors for the treatment of rheumatoid nodules.

作者信息

Bulbin Brianna, Kramer Neil, Rosenstein Elliot David, Rosenstein Rachel Kushner

机构信息

Hackensack Meridian School of Medicine, Hackensack University Medical Center, Nutley, New Jersey.

Division of Rheumatology, Department of Internal Medicine, Institute for Rheumatic & Autoimmune Diseases, Overlook Medical Center, Summit, New Jersey.

出版信息

JAAD Case Rep. 2025 Mar 14;59:113-116. doi: 10.1016/j.jdcr.2025.02.036. eCollection 2025 May.

DOI:10.1016/j.jdcr.2025.02.036
PMID:40290798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12022407/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/12022407/2c3e849da70b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/12022407/884b0d44a8f6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/12022407/2c3e849da70b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/12022407/884b0d44a8f6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2bd/12022407/2c3e849da70b/gr2.jpg

相似文献

1
JAK inhibitors for the treatment of rheumatoid nodules.用于治疗类风湿结节的JAK抑制剂。
JAAD Case Rep. 2025 Mar 14;59:113-116. doi: 10.1016/j.jdcr.2025.02.036. eCollection 2025 May.
2
JAK inhibitors for rheumatoid arthritis.用于类风湿性关节炎的JAK抑制剂。
Expert Opin Investig Drugs. 2023 Apr;32(4):333-344. doi: 10.1080/13543784.2023.2199919. Epub 2023 Apr 7.
3
New insights into IFN-γ in rheumatoid arthritis: role in the era of JAK inhibitors.类风湿关节炎中干扰素-γ的新见解：在JAK抑制剂时代的作用
Immunol Med. 2020 Jun;43(2):72-78. doi: 10.1080/25785826.2020.1751908. Epub 2020 Apr 25.
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JAK/STAT pathway and nociceptive cytokine signalling in rheumatoid arthritis and psoriatic arthritis.JAK/STAT 通路及痛觉细胞因子信号在类风湿关节炎和银屑病关节炎中的作用。
Clin Exp Rheumatol. 2021 May-Jun;39(3):668-675. doi: 10.55563/clinexprheumatol/e7ayu8. Epub 2020 Oct 30.
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Real-world study comparing the efficacy of Janus kinase inhibitors in patients with difficult-to-treat rheumatoid arthritis.真实世界研究比较了 Janus 激酶抑制剂在治疗困难的类风湿关节炎患者中的疗效。
Clin Rheumatol. 2024 Nov;43(11):3285-3292. doi: 10.1007/s10067-024-07117-w. Epub 2024 Sep 7.
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Janus kinase inhibitors for the treatment of rheumatoid arthritis demonstrate similar profiles of in vitro cytokine receptor inhibition.Janus 激酶抑制剂治疗类风湿关节炎的体外细胞因子受体抑制作用具有相似特征。
Pharmacol Res Perspect. 2019 Nov 15;7(6):e00537. doi: 10.1002/prp2.537. eCollection 2019 Dec.
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JAK-STAT inhibitors: Immersing therapeutic approach for management of rheumatoid arthritis.JAK-STAT 抑制剂：类风湿关节炎治疗管理的浸入式治疗方法。
Int Immunopharmacol. 2020 Sep;86:106731. doi: 10.1016/j.intimp.2020.106731. Epub 2020 Jun 23.
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JAK inhibitors differentially modulate B cell activation, maturation and function: A comparative analysis of five JAK inhibitors in an B cell differentiation model and in patients with rheumatoid arthritis.JAK 抑制剂对 B 细胞激活、成熟和功能的影响具有差异性：五种 JAK 抑制剂在 B 细胞分化模型和类风湿关节炎患者中的比较分析。
Front Immunol. 2023 Jan 26;14:1087986. doi: 10.3389/fimmu.2023.1087986. eCollection 2023.
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Advance in bone destruction participated by JAK/STAT in rheumatoid arthritis and therapeutic effect of JAK/STAT inhibitors.JAK/STAT 在类风湿关节炎中参与的骨破坏进展及 JAK/STAT 抑制剂的治疗效果。
Int Immunopharmacol. 2022 Oct;111:109095. doi: 10.1016/j.intimp.2022.109095. Epub 2022 Aug 1.
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Chemical JAK inhibitors for the treatment of rheumatoid arthritis.用于治疗类风湿性关节炎的化学JAK抑制剂。
Expert Opin Pharmacother. 2016 Nov;17(16):2215-2225. doi: 10.1080/14656566.2016.1241237. Epub 2016 Oct 8.

本文引用的文献

1
Seronegative cutaneous rheumatoid nodules with positive response to tofacitinib.对托法替布有阳性反应的血清阴性皮肤类风湿结节
JAAD Case Rep. 2024 Jun 10;50:88-90. doi: 10.1016/j.jdcr.2024.05.033. eCollection 2024 Aug.
2
A large pulmonary nodule in a rheumatoid arthritis patient treated with tofacitinib.一名类风湿关节炎患者在接受托法替布治疗后出现大的肺结节。
Int J Rheum Dis. 2024 Jan;27(1):e15013. doi: 10.1111/1756-185X.15013. Epub 2023 Dec 22.
3
Cutaneous Manifestations of Rheumatoid Arthritis: Diagnosis and Treatment.类风湿关节炎的皮肤表现：诊断与治疗
J Pers Med. 2023 Oct 10;13(10):1479. doi: 10.3390/jpm13101479.
4
Intravenous immunoglobulin-refractory necrobiotic xanthogranuloma successfully treated with tofacitinib 2% cream.用2%托法替布乳膏成功治疗静脉注射免疫球蛋白难治性坏死性黄色肉芽肿。
JAAD Case Rep. 2022 Dec 15;32:41-43. doi: 10.1016/j.jdcr.2022.12.002. eCollection 2023 Feb.
5
Treatment with biologic DMARDs may not adversely affect lung nodules in rheumatoid arthritis patients.使用生物性改善病情抗风湿药（DMARDs）进行治疗可能不会对类风湿关节炎患者的肺结节产生不利影响。
Eur J Rheumatol. 2022 Apr;9(2):75-81. doi: 10.5152/eujrheum.2022.21067.
6
A case of rheumatoid arthritis with multiple lung rheumatoid nodules successfully treated with tofacitinib.一例类风湿关节炎伴多发肺部类风湿结节患者经托法替布治疗后获得良好疗效。
Mod Rheumatol Case Rep. 2021 Jan;5(1):1-5. doi: 10.1080/24725625.2020.1777677. Epub 2020 Jun 17.
7
Massive nodulous lesions on hands and feet in a RA patient and improvement under baricitinib treatment.一名类风湿关节炎患者手足出现大量结节性病变，在巴瑞替尼治疗下病情改善。
RMD Open. 2020 Nov;6(3). doi: 10.1136/rmdopen-2020-001493.
8
The Promise of JAK Inhibitors for Treatment of Sarcoidosis and Other Inflammatory Disorders with Macrophage Activation: A Review of the Literature.JAK 抑制剂治疗伴有巨噬细胞活化的结节病和其他炎症性疾病的前景：文献综述。
Yale J Biol Med. 2020 Mar 27;93(1):187-195. eCollection 2020 Mar.
9
The role of the JAK/STAT signal pathway in rheumatoid arthritis.JAK/STAT信号通路在类风湿关节炎中的作用。
Ther Adv Musculoskelet Dis. 2018 Jun;10(5-6):117-127. doi: 10.1177/1759720X18776224. Epub 2018 May 19.
10
Rheumatoid Nodules.类风湿结节
Dermatol Clin. 2015 Jul;33(3):361-71. doi: 10.1016/j.det.2015.03.004.