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自发性出血性后弹力层脱离:影像学、诊断与治疗

Spontaneous hemorrhagic Descemet membrane detachment: Imaging, diagnosis, and management.

作者信息

Andersen Tomas, Barna Laura, Kanu Levi N

机构信息

Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

出版信息

Am J Ophthalmol Case Rep. 2025 Apr 14;38:102337. doi: 10.1016/j.ajoc.2025.102337. eCollection 2025 Jun.

DOI:10.1016/j.ajoc.2025.102337
PMID:40290852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12032173/
Abstract

PURPOSE

To describe unique features surrounding the etiology, diagnosis, and management of a rare presentation of hemorrhagic detachment of Descemet membrane.

OBSERVATIONS

A 91-year-old woman with chronic marginal corneal degeneration and corneal neovascularization of both eyes presented with hemorrhagic detachment of Descemet membrane of the right eye.

CONCLUSIONS AND IMPORTANCE

This case highlights the need to consider pre-Descemet hemorrhage on the differential diagnosis for anterior segment hemorrhage even in the absence of risk factors such as surgery and trauma. This case, initially thought to represent a hyphema, underscores the importance of anterior segment imaging in accurate diagnosis and monitoring of this condition. Lastly, this case illustrates a management approach that successfully cleared the hemorrhage, reattached Descemet membrane, and restored visual acuity without keratoplasty.

摘要

目的

描述Descemet膜出血性脱离这一罕见表现的病因、诊断及处理方面的独特特征。

观察结果

一名91岁患有双眼慢性边缘性角膜变性和角膜新生血管的女性,出现右眼Descemet膜出血性脱离。

结论及重要性

该病例强调,即使在没有手术和外伤等危险因素的情况下,对于前段出血的鉴别诊断也需要考虑Descemet膜前出血。该病例最初被认为是前房积血,强调了前段成像在准确诊断和监测这种情况中的重要性。最后,该病例说明了一种成功清除出血、使Descemet膜复位并在不进行角膜移植的情况下恢复视力的处理方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4426/12032173/4f4ce4b1c1c3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4426/12032173/322d0959cb40/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4426/12032173/4f4ce4b1c1c3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4426/12032173/322d0959cb40/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4426/12032173/4f4ce4b1c1c3/gr2.jpg

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本文引用的文献

1
Descemet's Membrane Detachment during Phacocanaloplasty: Case Series and In-Depth Literature Review.超声乳化房角成形术期间的后弹力层脱离:病例系列及深入文献综述
J Clin Med. 2023 Aug 23;12(17):5461. doi: 10.3390/jcm12175461.
2
Bedside anterior segment optical coherence tomography-assisted reattachment of severe hemorrhagic Descemet's membrane detachment after ab externo 360-degree suture trabeculotomy combined with trabeculectomy.床旁眼前节光学相干断层扫描辅助下360度外路小梁切开联合小梁切除术后严重出血性Descemet膜脱离的复位术
Int J Ophthalmol. 2023 Feb 18;16(2):316-319. doi: 10.18240/ijo.2023.02.22. eCollection 2023.
3
Treatment for Intracorneal Hematoma by Anterior Chamber Gas Tamponade Combined With Keratocentesis.
前房气体填充联合角膜穿刺术治疗角膜内血肿。
Eye Contact Lens. 2023 Jan 1;49(1):42-44. doi: 10.1097/ICL.0000000000000959. Epub 2022 Nov 16.
4
Hemorrhagic Descemet's Membrane Detachment in Nonpenetrating Glaucoma Surgery.非穿透性青光眼手术中出血性Descemet膜脱离
J Glaucoma. 2021 Jul 1;30(7):e352-e356. doi: 10.1097/IJG.0000000000001721.
5
Hemorrhagic Descemet Membrane Detachment during Ab Interno Canaloplasty.内路小梁切开术期间的出血性后弹力层脱离
Case Rep Ophthalmol Med. 2019 Apr 21;2019:3653954. doi: 10.1155/2019/3653954. eCollection 2019.
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Intraepithelial corneal haemorrhage in a rigid contact lens wearer.佩戴硬性角膜接触镜者的角膜上皮内出血。
Cont Lens Anterior Eye. 2018 Oct;41(5):455-457. doi: 10.1016/j.clae.2018.03.003. Epub 2018 Mar 24.
7
Intracorneal Hematoma After Ahmed Glaucoma Valve Implant Surgery.艾哈迈德青光眼引流阀植入术后角膜内血肿
J Glaucoma. 2017 Sep;26(9):e202-e204. doi: 10.1097/IJG.0000000000000693.
8
Novel Treatment for Hemorrhagic Descemet Detachment After Canaloplasty.小梁切开术后出血性后弹力层脱离的新型治疗方法。
Cornea. 2015 Dec;34(12):1611-2. doi: 10.1097/ICO.0000000000000636.
9
Spontaneous hemorrhagic Descemet membrane detachment causing pupillary block.自发性出血性后弹力层脱离导致瞳孔阻滞。
Eur J Ophthalmol. 2012 Sep-Oct;22(5):819-22. doi: 10.5301/ejo.5000164.
10
Corneal blood staining secondary to hemorrhagic descemet membrane detachment.出血性后弹力层脱离继发的角膜血染
Cornea. 2007 Dec;26(10):1273-4. doi: 10.1097/ICO.0b013e318148bd80.