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这个婴儿正在发生中风:一个说明性病例报告。

This infant is having a stroke: an illustrative case report.

机构信息

Department of Paediatric Emergency Medicine, Children's Health Ireland at Crumlin, Dublin, Ireland.

School of Medicine, Women's and Children's Health, University College Dublin, Dublin, Ireland.

出版信息

Ir J Med Sci. 2023 Oct;192(5):2467-2473. doi: 10.1007/s11845-022-03236-y. Epub 2022 Dec 1.

DOI:10.1007/s11845-022-03236-y
PMID:36451003
Abstract

BACKGROUND

Paediatric stroke is a rare event, and timely intervention is required to minimise long-term disability, reduced quality of life and financial implications. Although reperfusion strategies such as thrombolysis and thrombectomy are now well established in the adult population, and paediatric consensus guidelines allow for reperfusion therapies in children, access is currently limited due to diagnostic delays. This challenge is partly due to the rarity of presentation, infrastructure and public awareness to support early diagnosis as exists in the adult setting. We use an illustrative case and literature to describe an achieved case of paediatric stroke within an Irish setting.

METHODS

We use the case of an 8-month-old male infant presenting with acute-onset left-sided hemiplegia to illustrate what can be achieved in an Irish setting.

RESULTS

Stroke was identified quickly following presentation, timely neuroimaging and multidisciplinary involvement with disposition to paediatric intensive care unit where thrombolysis was administered. Although the patient has some speech delay, he is recovering well with normal gross motor function.

CONCLUSIONS

Paediatric stroke care should be available to all children presenting with acute stroke symptoms; however, the rarity of the diagnosis would suggest a national strategy will be required to provide equitable care at a national level.

摘要

背景

儿科中风是一种罕见的疾病,需要及时干预以最小化长期残疾、生活质量下降和经济影响。尽管溶栓和取栓等再灌注策略在成人中已得到广泛应用,并且儿科共识指南允许对儿童进行再灌注治疗,但由于诊断延迟,目前这些治疗方法的应用受到限制。这种挑战部分归因于与成人环境中存在的支持早期诊断的基础设施、公众意识和诊断延迟有关的罕见表现。我们使用一个说明性的病例和文献来描述爱尔兰儿科中风的一个成功病例。

方法

我们使用一名 8 个月大的男性婴儿出现急性左侧偏瘫的病例来说明在爱尔兰环境中可以实现什么。

结果

患者在出现症状后迅速诊断出中风,及时进行神经影像学检查,并多学科参与,将其转至儿科重症监护病房进行溶栓治疗。尽管患者存在一些言语延迟,但他的恢复情况良好,运动功能正常。

结论

所有出现急性中风症状的儿童都应能获得儿科中风治疗;然而,由于这种诊断非常罕见,因此需要制定国家策略,以在全国范围内提供公平的护理。

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Interv Neuroradiol. 2019 Oct;25(5):516-520. doi: 10.1177/1591019919844946. Epub 2019 May 9.
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Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association.新生儿和儿童脑卒中的管理:美国心脏协会/美国卒中协会的科学声明。
Stroke. 2019 Mar;50(3):e51-e96. doi: 10.1161/STR.0000000000000183.
3
What Will Improve Pediatric Acute Stroke Care?
如何改善儿童急性中风护理?
Stroke. 2019 Feb;50(2):249-256. doi: 10.1161/STROKEAHA.118.022881.
4
The "National Integrated Medical Imaging System" [NIMIS]-friend, not nimesis!“国家综合医学成像系统”[NIMIS]——是朋友,而非对手!
Ir J Med Sci. 2019 May;188(2):365-369. doi: 10.1007/s11845-018-1900-4. Epub 2018 Sep 15.
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A child with atypically subtle clinical presentation of acute arterial ischaemic stroke in the middle cerebral artery.一名患有大脑中动脉急性动脉缺血性卒中,临床表现不典型且较为隐匿的儿童。
Interv Neuroradiol. 2018 Dec;24(6):684-687. doi: 10.1177/1591019918790241. Epub 2018 Jul 22.
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Feasibility, safety, and outcome of recanalization treatment in childhood stroke.儿童脑卒中血管再通治疗的可行性、安全性和结局。
Ann Neurol. 2018 Jun;83(6):1125-1132. doi: 10.1002/ana.25242.
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Pediatric Stroke and Its Mimics: Limitations of a Pediatric Stroke Clinical Pathway.儿科中风及其类似疾病:儿科中风临床路径的局限性。
Pediatr Neurol. 2018 Mar;80:35-41. doi: 10.1016/j.pediatrneurol.2017.10.005. Epub 2017 Oct 31.
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Pediatric Stroke Clinical Pathway Improves the Time to Diagnosis in an Emergency Department.儿科卒中临床路径缩短了急诊科的诊断时间。
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Stroke. 2016 Oct;47(10):2476-81. doi: 10.1161/STROKEAHA.116.014179. Epub 2016 Sep 6.
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