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一名患有左心室肥厚的透析患者动静脉内瘘重新开放后出现严重左心室流出道梗阻

Severe Left Ventricular Outflow Tract Obstruction Following Arteriovenous Fistula Reopening in a Dialysis Patient With Left Ventricular Hypertrophy.

作者信息

Rachid Abbas, Chaaban Batoul, Mohammed Malek, Khalil Nina M, Kazma Hasan

机构信息

Internal Medicine, Lebanese University, Beirut, LBN.

Cardiology, Lebanese University, Beirut, LBN.

出版信息

Cureus. 2025 Mar 27;17(3):e81284. doi: 10.7759/cureus.81284. eCollection 2025 Mar.

Abstract

Arteriovenous fistulas (AVFs) are the preferred vascular access for hemodialysis due to their durability and lower risk of complications than alternative access methods. However, AVFs can significantly impact cardiac function, particularly in patients with preexisting cardiovascular conditions. We present a case of a 56-year-old female with a history of hypertension and end-stage renal disease who developed recurrent hypotension, dizziness, and dyspnea following AVF reopening. The echocardiographic evaluation revealed severe left ventricular hypertrophy, systolic anterior motion of the mitral valve, significant mitral regurgitation, and left ventricular outflow tract (LVOT) obstruction with a high-pressure gradient. Despite medical management with beta-blockers, symptoms persisted, leading to the decision to close the AVF surgically. Following AVF closure, echocardiography showed a marked improvement in mitral regurgitation and resolution of LVOT obstruction, with the patient tolerating subsequent dialysis without complications. This case highlights the potential hemodynamic consequences of AVF reopening in patients with underlying cardiac pathology and emphasizes the need for careful cardiovascular evaluation.

摘要

动静脉内瘘(AVF)因其耐用性以及相较于其他血管通路方法并发症风险较低,而成为血液透析的首选血管通路。然而,动静脉内瘘会显著影响心脏功能,尤其是在已有心血管疾病的患者中。我们报告一例56岁女性病例,该患者有高血压和终末期肾病病史,在动静脉内瘘重新开放后出现反复低血压、头晕和呼吸困难。超声心动图评估显示严重左心室肥厚、二尖瓣收缩期前向运动、明显二尖瓣反流以及左心室流出道(LVOT)梗阻并伴有高压梯度。尽管使用β受体阻滞剂进行药物治疗,但症状持续存在,因此决定通过手术关闭动静脉内瘘。动静脉内瘘关闭后,超声心动图显示二尖瓣反流明显改善,左心室流出道梗阻解除,患者能够耐受后续透析且无并发症。该病例突出了潜在心脏病变患者动静脉内瘘重新开放可能产生的血流动力学后果,并强调了进行仔细心血管评估的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64fb/12034342/b49f1db0de5b/cureus-0017-00000081284-i01.jpg

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