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终末期肾病患者动静脉瘘的心脏并发症

Cardiac complications of arteriovenous fistulas in patients with end-stage renal disease.

作者信息

Alkhouli Mohamad, Sandhu Paul, Boobes Khlaed, Hatahet Kamel, Raza Farhan, Boobes Yousef

机构信息

Cardiology Department, University of Rochester, Rochester, NY, USA.

Department of Internal Medicine, Boston University, Boston, MA, USA.

出版信息

Nefrologia. 2015;35(3):234-45. doi: 10.1016/j.nefro.2015.03.001. Epub 2015 Jun 23.

Abstract

Cardiovascular disease is the leading cause of the death in dialysis patients. Arteriovenous fistulas (AVFs) are associated with lower mortality and are viewed as the desired access option in most patients with advanced kidney disease needing dialysis. However, AVFs have significant and potentially deleterious effects on cardiac functions particularly in the setting of preexisting heart disease. This article provides a comprehensive and contemporary review to what is known about the impact of AVFs on: congestive heart failure, left ventricular hypertrophy, pulmonary hypertension, right ventricular dysfunction, coronary artery disease and valvular heart disease.

摘要

心血管疾病是透析患者死亡的主要原因。动静脉内瘘(AVF)与较低的死亡率相关,并且在大多数需要透析的晚期肾病患者中被视为理想的血管通路选择。然而,动静脉内瘘对心脏功能有显著且潜在的有害影响,尤其是在已有心脏病的情况下。本文对动静脉内瘘在以下方面的影响进行了全面且与时俱进的综述:充血性心力衰竭、左心室肥厚、肺动脉高压、右心室功能障碍、冠状动脉疾病和心脏瓣膜病。

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