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一种恶性伪装:表现为腹主动脉瘤即将破裂的血管肉瘤。

A Malignant Masquerade: Angiosarcoma Presenting as an Impending Rupture of an Abdominal Aortic Aneurysm.

作者信息

Tamaoka Koki, Shimamoto Takeshi, Sakamoto Kazuhisa, Takehara Makoto

机构信息

Cardiovascular Surgery, Hamamatsu Rosai Hospital, Hamamatsu, JPN.

出版信息

Cureus. 2025 Mar 26;17(3):e81233. doi: 10.7759/cureus.81233. eCollection 2025 Mar.

Abstract

Primary tumors arising from within the arterial wall are extremely uncommon and often present at advanced stages, making timely intervention challenging. Surgeons need to be aware of these rare conditions, as early detection and treatment can significantly improve patient outcomes. Angiosarcoma of the abdominal aorta is a particularly rare and aggressive malignancy, often resembling an aneurysm at risk of rupture. A 59-year-old woman presented with sudden onset of severe abdominal pain and was diagnosed with a 42 mm saccular abdominal aortic aneurysm, which was urgently repaired under the presumption of impending rupture. Intraoperatively, we found the aneurysm to be notably more fragile than a typical abdominal aortic aneurysm, while the rest of the aorta appeared healthy. This discrepancy raised suspicion of an atypical lesion, prompting us to resect the aneurysm and submit it for pathology. Subsequent immunohistochemical staining confirmed angiosarcoma, enabling timely referral for oncological management. Angiosarcoma is often difficult to diagnose based on computed tomography findings alone, so any atypical appearance of the aorta should raise suspicion of this malignancy, even in emergent surgery. This case shows the important role of careful intraoperative assessment and pathological examination in guiding definitive management.

摘要

起源于动脉壁的原发性肿瘤极为罕见,且通常在晚期才出现,这使得及时干预具有挑战性。外科医生需要了解这些罕见病症,因为早期发现和治疗可显著改善患者预后。腹主动脉血管肉瘤是一种极其罕见且侵袭性强的恶性肿瘤,常类似有破裂风险的动脉瘤。一名59岁女性突发剧烈腹痛,被诊断为42毫米的囊状腹主动脉瘤,鉴于有即将破裂的可能,紧急进行了修复手术。术中,我们发现该动脉瘤比典型的腹主动脉瘤明显更脆弱,而主动脉的其余部分看起来健康。这种差异引发了对非典型病变的怀疑,促使我们切除动脉瘤并送去做病理检查。随后的免疫组化染色证实为血管肉瘤,从而能够及时转诊进行肿瘤治疗。仅根据计算机断层扫描结果,血管肉瘤往往难以诊断,所以即使在急诊手术中,主动脉的任何非典型表现都应引起对这种恶性肿瘤的怀疑。本病例显示了术中仔细评估和病理检查在指导最终治疗中的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b470/12025343/6b309d854995/cureus-0017-00000081233-i01.jpg

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