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表现为全葡萄膜炎的癌症相关性视网膜病变继发于微小浸润性滤泡状甲状腺癌

Cancer-Associated Retinopathy Presenting as Panuveitis Secondary to Minimally Invasive Follicular Thyroid Carcinoma.

作者信息

Arnold Natalie, Mishra Amit, Seamone Mark

机构信息

Department of Ophthalmology and Visual Sciences, University of Alberta, AB, Canada.

出版信息

J Vitreoretin Dis. 2025 Apr 25:24741264251337108. doi: 10.1177/24741264251337108.

Abstract

To describe a case of cancer-associated retinopathy (CAR) secondary to follicular thyroid carcinoma. A single retrospective case was evaluated. A 68-year-old woman presented with floaters and decreased vision in the right eye and was found to have panuveitis. The left eye subsequently developed panuveitis 6 months later, ultimately resulting in retinal atrophy. Extensive investigations, including vitreous biopsies, imaging, and positron emission tomography, led to a diagnosis of CAR secondary to minimally invasive follicular thyroid carcinoma with serology positive for anti-enolase, anti-HSP60, and anti-glyceraldehyde-3-phosphate dehydrogenase. Cases of CAR secondary to minimally invasive follicular thyroid carcinoma are rare. Ensuring an early diagnosis and promptly initiating treatment, with a goal of preserving sight, are imperative.

摘要

描述一例继发于滤泡性甲状腺癌的癌症相关性视网膜病变(CAR)。评估了一例回顾性病例。一名68岁女性因右眼出现飞蚊症和视力下降就诊,被发现患有全葡萄膜炎。6个月后左眼也出现了全葡萄膜炎,最终导致视网膜萎缩。广泛的检查,包括玻璃体活检、影像学检查和正电子发射断层扫描,诊断为继发于微小浸润性滤泡性甲状腺癌的CAR,血清学检查显示抗烯醇化酶、抗HSP60和抗甘油醛-3-磷酸脱氢酶呈阳性。继发于微小浸润性滤泡性甲状腺癌的CAR病例罕见。确保早期诊断并及时开始治疗以保住视力至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c02/12031738/97daf3d571cc/10.1177_24741264251337108-fig1.jpg

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