Arnold Natalie, Mishra Amit, Seamone Mark
Department of Ophthalmology and Visual Sciences, University of Alberta, AB, Canada.
J Vitreoretin Dis. 2025 Apr 25:24741264251337108. doi: 10.1177/24741264251337108.
To describe a case of cancer-associated retinopathy (CAR) secondary to follicular thyroid carcinoma. A single retrospective case was evaluated. A 68-year-old woman presented with floaters and decreased vision in the right eye and was found to have panuveitis. The left eye subsequently developed panuveitis 6 months later, ultimately resulting in retinal atrophy. Extensive investigations, including vitreous biopsies, imaging, and positron emission tomography, led to a diagnosis of CAR secondary to minimally invasive follicular thyroid carcinoma with serology positive for anti-enolase, anti-HSP60, and anti-glyceraldehyde-3-phosphate dehydrogenase. Cases of CAR secondary to minimally invasive follicular thyroid carcinoma are rare. Ensuring an early diagnosis and promptly initiating treatment, with a goal of preserving sight, are imperative.
描述一例继发于滤泡性甲状腺癌的癌症相关性视网膜病变(CAR)。评估了一例回顾性病例。一名68岁女性因右眼出现飞蚊症和视力下降就诊,被发现患有全葡萄膜炎。6个月后左眼也出现了全葡萄膜炎,最终导致视网膜萎缩。广泛的检查,包括玻璃体活检、影像学检查和正电子发射断层扫描,诊断为继发于微小浸润性滤泡性甲状腺癌的CAR,血清学检查显示抗烯醇化酶、抗HSP60和抗甘油醛-3-磷酸脱氢酶呈阳性。继发于微小浸润性滤泡性甲状腺癌的CAR病例罕见。确保早期诊断并及时开始治疗以保住视力至关重要。