Cao Jialin, Gan Hui, Wu Jian-Hui, Yuan Yue, Ye Fei
The First Clinical Medical College of Guangdong Medical University, Zhanjiang, Guangdong 524000, P. R. China.
The First Affiliated Hospital of Guangzhou Medical University, 510180, Guangzhou, Guangdong, P. R. China.
Open Life Sci. 2025 Apr 14;20(1):20221041. doi: 10.1515/biol-2022-1041. eCollection 2025.
Multiple cases of extrapulmonary tuberculosis (TB) combined with pulmonary TB are commonly encountered in clinical practice. Nasopharyngeal TB is often ignored because of its hidden location and nonspecific manifestations. A correlation between cervical lymph node and nasopharyngeal TB has been observed; however, reports of cervical lymph node TB complicated with nasopharyngeal TB are rare, potentially leading to missed diagnosis. Herein, we present a case of nasopharyngeal TB combined with cervical lymph node and pulmonary TB. Radiographic findings consistently suggested TB, although multiple smear tests' results were negative. After 3 months of diagnostic anti-TB treatment, the nasopharyngeal TB completely disappeared, and the swollen cervical lymph nodes subsided after 1 year of treatment. This case report deepens our understanding of nasopharyngeal TB and emphasizes the need for nasal endoscopy in patients with cervical lymph node TB.
在临床实践中，肺外结核（TB）合并肺结核的病例屡见不鲜。鼻咽结核因其位置隐匿和临床表现不具特异性，常被忽视。已观察到颈部淋巴结与鼻咽结核之间存在关联；然而，颈部淋巴结结核合并鼻咽结核的报道罕见，这可能导致漏诊。在此，我们报告一例鼻咽结核合并颈部淋巴结结核及肺结核的病例。尽管多次涂片检查结果均为阴性，但影像学表现始终提示为结核。经过3个月的诊断性抗结核治疗，鼻咽结核完全消失，治疗1年后肿大的颈部淋巴结消退。本病例报告加深了我们对鼻咽结核的认识，并强调了对颈部淋巴结结核患者进行鼻内镜检查的必要性。
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