老年人：75岁之后结肠镜筛查还有作用吗？外科医生的观点。
The Old: Is There Any Role for Screening Colonoscopy after the Age of 75? The Surgeon's Perspective.
作者信息
Khan Imran, Belkovsky Mikhael, Gorgun Emre
机构信息
Department of Colorectal Surgery, Digestive Diseases Institute, Cleveland Clinic, Cleveland, Ohio.
出版信息
Clin Colon Rectal Surg. 2024 Jun 27;38(3):212-218. doi: 10.1055/s-0044-1787893. eCollection 2025 May.
Abstract
Guidelines recommend individualized decision making for screening colonoscopy for colorectal cancer (CRC) in patients after the age of 75 years due to low additional benefits. That should be taken with a grain of salt, as these recommendations are based on expert opinion and simulation models which do not consider (1) the differences in pathogenesis and cancer biology of CRC in elderly; (2) the risks of colonoscopy in this patient population; (3) and the impact of new surgical and nonsurgical therapies for CRC. In this review, our goal is to bring a surgeon's perspective to understand the role of screening colonoscopy in patients older than 75 years.
摘要
由于额外获益较低，指南建议对75岁以上患者进行结肠镜筛查结直肠癌（CRC）时应个体化决策。但对此应持保留态度，因为这些建议基于专家意见和模拟模型，未考虑：（1）老年患者CRC发病机制和癌症生物学的差异；（2）该患者群体进行结肠镜检查的风险；（3）CRC新的手术和非手术治疗的影响。在本综述中，我们的目标是从外科医生的角度来理解结肠镜筛查在75岁以上患者中的作用。
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